Diagnostic challenges in primary cardiac lymphoma, the opportunity of 18F-FDG PET/CT integrated with contrast-enhanced CT
Diagnostic challenges in primary cardiac lymphoma, the opportunity of 18F-FDG PET/CT integrated with contrast-enhanced CT
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原发性心脏淋巴瘤的诊断挑战，18F-FDG PET/CT 与增强 CT 相结合的机遇
DOI：
10.1007/s12350-021-02723-6
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发表时间：
2021-07
期刊：
影响因子：
--
通讯作者：
Zaiyi Liu
中科院分区：
文献类型：
--
作者：
Entao Liu;Jia Huang;Haojian Dong;Zerui Chen;Chao Liu;Qiu Xie;Weiping Xu;Shuxia Wang;Zaiyi Liu
背景：本研究的目的是回顾性评价18f - fdg PET/CT结合对比增强CT （CECT）在原发性心脏淋巴瘤（pcl）和原发性心脏血管肉瘤（PCAs）鉴别诊断中的价值。方法：收集pcl和PCAs患者的临床和影像学资料。所有患者术前均行18f - fdg PET/CT和胸部CECT检查。利用CECT图像分析增强模式和肿瘤形态。分析心脏病变的PET强度和体积参数。评估了各参数的性能特征。结果：对9例PCL患者和8例PCA患者进行分析。在SUVmax （t = 3.790, P = 0.002）、SUVmean （t = 4.273, P = 0.001）、代谢肿瘤体积（U = 13.00, P = 0.027）、瘤肝比（U = 10.00, P = 0.011）、病灶糖酵解总量（U = 4.0, P = 0.001）方面，pcl与PC18As之间存在显著差异。两组在肿瘤增强模式（P = 0.002）和肿瘤形态（P = 0.015）上差异有统计学意义。F-FDG PET/CT联合CECT提高了诊断准确率，联合截止率（SUVmean > 5.17）可达到100%，但差异无统计学意义（P > 0.05）。结论：PCL的PET参数明显高于PCA的PET参数。增强模式和肿瘤形态也不同。根据这些特征，可以区分两种最常见的原发性心脏恶性肿瘤。
Background:The purpose of this study was to retrospectively evaluate the value of18F-FDG PET/CT integrated with contrast-enhanced CT (CECT) in the differential diagnosis of primary cardiac lymphomas (PCLs) and primary cardiac angiosarcomas (PCAs).Methods:Clinical and imaging data of patients with PCLs and PCAs were collected. All patients underwent preoperative18F-FDG PET/CT and thoracic CECT. The enhancement pattern and tumor morphology were analyzed using CECT images. The intensity- and volume-based PET parameters of cardiac lesions were analyzed. The performance characteristics of all parameters were assessed.Results:Nine patients with PCL and eight patients with PCA were analyzed. There were significant differences in SUVmax (t = 3.790, P = .002), SUVmean (t = 4.273, P = .001), metabolic tumor volume (U = 13.00, P = .027), tumor-to-liver ratio (U = 10.00, P = .011), and total lesion glycolysis (U = 4.0, P = .001) between PCLs and PC18As. There were significant differences in the enhancement pattern of tumors (P = .002) and tumor morphology (P = .015). The combination of F-FDG PET/CT and CECT improved the diagnostic accuracy, and the combination cutoff (SUVmean > 5.17) could reach 100%, but the difference was not statistically significant (P > .05).Conclusion:The intensity- and volume-based PET parameters of PCL were significantly higher than those of PCA. The enhancement pattern and tumor morphology were also different. According to these characteristics, the two most common types of primary cardiac malignancies can be differentiated.
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DOI：
10.1093/ehjci/jez324
发表时间：
2020-01
期刊：
European heart journal cardiovascular Imaging
影响因子：
--
作者：
Stephani C. Wang;Chris W. Pan
通讯作者：
Stephani C. Wang;Chris W. Pan
影响因子：
4.8
作者：
Kang JH;Youk JH;Kim JA;Gweon HM;Eun NL;Ko KH;Son EJ
通讯作者：
Son EJ
DOI：
10.1007/s00259-013-2436-5
发表时间：
2013-09-01
影响因子：
9.1
作者：
Kikuchi, Yasuka;Oyama-Manabe, Noriko;Shirato, Hiroki
通讯作者：
Shirato, Hiroki
影响因子：
3.5
作者：
Miguel, Carlos E.;Bestetti, Reinaldo B.
通讯作者：
Bestetti, Reinaldo B.
影响因子：
3.8
作者：
Bonou, Maria;Kapelios, Chris J.;Viniou, Nora-Athina
通讯作者：
Viniou, Nora-Athina