Polydendrocytes in development and myelin repair.
Polydendrocytes in development and myelin repair.
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DOI:
10.1007/s12264-013-1320-4
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发表时间:
2013-04
影响因子:
5.6
通讯作者:
Nishiyama, Akiko
中科院分区:
文献类型:
--
作者:
Zuo, Hao;Nishiyama, Akiko
Polydendrocytes (NG2 cells) are a distinct type of glia that populate the developing and adult central nervous systems (CNS). In the adult CNS, they retain mitotic activity and represent the largest proliferating cell population. Genetic and epigenetic mechanisms regulate the fate of polydendrocytes, which give rise to both oligodendrocytes and astrocytes. In addition, polydendrocytes actively differentiate into myelin-forming oligodendrocytes in response to demyelination. This review summarizes the current knowledge regarding polydendrocyte development, which provides an important basis for understanding the mechanisms that lead to the remyelination of demyelinated lesions.
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影响因子:
7.8
作者:
Aguirre, Adan A;Chittajallu, Ramesh;Belachew, Shibeshih;Gallo, Vittorio
通讯作者:
Gallo, Vittorio
影响因子:
7.8
作者:
Genoud, Stephane;Lappe-Siefke, Corinna;Goebbels, Sandra;Radtke, Freddy;Aguet, Michel;Scherer, Steven S;Suter, Ueli;Nave, Klaus-Armin;Mantei, Ned
通讯作者:
Mantei, Ned
影响因子:
4.6
作者:
Budde, Holger;Schmitt, Sebastian;Simons, Mikael
通讯作者:
Simons, Mikael
DOI:
10.1523/jneurosci.1759-11.2011
发表时间:
2011-08-17
期刊:
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子:
--
作者:
Guo F;Maeda Y;Ma J;Delgado M;Sohn J;Miers L;Ko EM;Bannerman P;Xu J;Wang Y;Zhou C;Takebayashi H;Pleasure D
通讯作者:
Pleasure D
影响因子:
158.5
作者:
Chang, A;Tourtellotte, WW;Trapp, BD
通讯作者:
Trapp, BD