Sex hormones in alcohol consumption: a systematic review of evidence.
Sex hormones in alcohol consumption: a systematic review of evidence.
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DOI：
10.1111/adb.12589
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发表时间：
2019-03
影响因子：
3.4
通讯作者：
Karpyak VM
中科院分区：
文献类型：
--
作者：
Erol A;Ho AM;Winham SJ;Karpyak VM
Sex hormones play an important role in establishing sex‐distinctive brain structural and functional variations that could contribute to the sex differences in alcohol consumption behavior. Here, we systematically reviewed articles that studied sex hormone impacts on alcohol consumption and alcohol use disorder (AUD). An extensive literature search conducted in MEDLINE, PubMed, Scopus and CINAHL databases identified 776 articles, which were then evaluated for pre‐specified criteria for relevance and quality assurance. A total of 50 articles, including 19 human studies and 31 animal studies, were selected for this review. Existing evidence supports the association of increased testosterone level and increased risk for alcohol use and AUD in males but results are inconclusive in females. In contrast, the evidence supports the association of increased estrogen level and increased alcohol use in females, with mixed findings reported in males. Much less is known about the impact of progestins on alcohol use and misuse in human subjects. Future observational and experimental studies conducted in both sexes with a comprehensive hormone panel are needed to elucidate the impact of the interplay between various sex hormone levels during various developmental stages on alcohol use‐related phenotypes and AUD.
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影响因子：
3.2
作者：
Garbusow, Maria;Sebold, Miriam;Heinz, Andreas
通讯作者：
Heinz, Andreas
影响因子：
2.7
作者：
Ford, Matthew M.;Mark, Gregory P.;Finn, Deborah A.
通讯作者：
Finn, Deborah A.
DOI：
10.1097/00000374-200205000-00007
发表时间：
2002-05-01
影响因子：
3.2
作者：
Ford, MM;Eldridge, JC;Samson, HH
通讯作者：
Samson, HH
影响因子：
4.7
作者：
Braams, Barbara R.;Peper, Jiska S.;Crone, Eveline A.
通讯作者：
Crone, Eveline A.
DOI：
10.1111/j.1530-0277.1985.tb05584.x
发表时间：
1985-01-01
期刊：
ALCOHOL-CLINICAL AND EXPERIMENTAL RESEARCH
影响因子：
--
作者：
HARVEY, SM;BECKMAN, LJ
通讯作者：
BECKMAN, LJ