Minimum Information About a Microarray Experiment (MIAME)--successes, failures, challenges.

Minimum Information About a Microarray Experiment (MIAME)--successes, failures, challenges.
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DOI:
10.1100/tsw.2009.57
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发表时间:
2009-05-29
影响因子:
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通讯作者:
Brazma A
Brazma A
中科院分区:
其他
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作者:
Brazma A

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关于微阵列实验的最小信息(称为MIAME)指南描述了需要提供的信息,以便能够明确地解释基于微阵列的实验的结果。MIAME指南由微阵列基因表达数据(MGED)学会制定。自从2001年MIAME的立场论文发表以来,它在科学文献中被引用了一千多次。MIAME已经被许多其他技术复制,主要的数据存储库正在支持MIAME,大多数科学期刊都将MIAME指南作为出版要求。随着新一代测序技术的到来,MIAME面临着新的挑战。为了解决这个问题,MGED学会提出了新的指导方针,即关于高通量测序实验的最小信息(MINSEQE)。在这里,我们分析了MIAME成功的原因,并讨论了它的失败之处和面临的挑战。
The Minimum Information About a Microarray Experiment (known as MIAME) guidelines describe information that needs to be provided to enable the interpretation of the results of a microarray-based experiment unambiguously. The MIAME guidelines were developed by the Microarray Gene Expression Data (MGED) Society. Since the MIAME position paper was published in 2001, it has been cited in the scientific literature well over a thousand times. MIAME has been replicated for many other technologies, the major data repositories are supporting MIAME, and most scientific journals have adopted MIAME guidelines as a requirement for publishing. With the advent of new-generation sequencing technology, MIAME faces new challenges. To address this, the MGED Society has proposed new guidelines, i.e., Minimum Information about a high-throughput SeQuencing Experiment (MINSEQE). Here we present analysis of the reasons for the success of MIAME, as well as discuss where it has failed, and the challenges it faces.
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