Sensitive Detection of SARS-CoV-2-Specific Antibodies in Dried Blood Spot Samples.

Sensitive Detection of SARS-CoV-2-Specific Antibodies in Dried Blood Spot Samples.
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DOI:
10.3201/eid2612.203309
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发表时间:
2020-12
影响因子:
11.8
通讯作者:
O'Shea MK
O'Shea MK
中科院分区:
医学2区
文献类型:
--
作者:
Morley GL;Taylor S;Jossi S;Perez-Toledo M;Faustini SE;Marcial-Juarez E;Shields AM;Goodall M;Allen JD;Watanabe Y;Newby ML;Crispin M;Drayson MT;Cunningham AF;Richter AG;O'Shea MK

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干血斑(DBS)样本可用于检测严重急性呼吸综合征冠状病毒2型刺突抗体。DBS采样与匹配的血清样本相比具有相对98.1%的灵敏度和100%的特异度。因此,DBS抽样为冠状病毒大流行的全人群血清学检测提供了另一种选择。
Dried blood spot (DBS) samples can be used for the detection of severe acute respiratory syndrome coronavirus 2 spike antibodies. DBS sampling is comparable to matched serum samples with a relative 98.1% sensitivity and 100% specificity. Thus, DBS sampling offers an alternative for population-wide serologic testing in the coronavirus pandemic.
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