Meningococcemia due to the 2000 Hajj-associated outbreak strain (Serogroup W-135 ST-11) with immunoreactive complications.
Meningococcemia due to the 2000 Hajj-associated outbreak strain (Serogroup W-135 ST-11) with immunoreactive complications.
复制标题
脑膜炎球菌血症由 2000 年朝觐相关爆发菌株（血清群 W-135 ST-11）引起，并伴有免疫反应性并发症。
DOI：
10.7883/yoken.66.443
复制
发表时间：
2013
影响因子：
2.2
通讯作者：
N. Ohmagari
中科院分区：
文献类型：
--
作者：
Kei Yamamoto;Y. Kato;T. Shindo;M. Ujiie;Nozomi Takeshita;Shuzo Kanagawa;Junwa Kunimatsu;Yuiichi Tamori;T. Kano;R. Okuno;Hideyuki Takahashi;N. Ohmagari
我们报告了日本首例脑膜炎奈瑟菌血清群W-135序列型（ST）-11全身感染病例。一位44岁女性，因高热、喉咙痛、乏力就诊，被诊断为N。脑膜炎菌血症经聚合酶链反应和多位点序列分型鉴定，该菌株为血清群W-135 ST-11。治疗后约1个月，患者出现高热、呼吸困难、胸痛和肩痛，原因包括心包炎、多关节炎和腱鞘炎，这些都是W-135 ST-11脑膜炎球菌感染的相对常见的免疫反应性并发症。这种致病菌株与2000年朝觐朝圣者中爆发脑膜炎的菌株相同。该菌株目前在世界范围内发现，因为它可以达到高携带率，并具有长时间的携带。我们怀疑病人的感染是从一个进口的慢性带菌者那里获得的。
We present the first reported case of systemic infection with Neisseria meningitidis serogroup W-135 sequence type (ST)-11 in Japan. A 44-year-old woman presented with high fever, sore throat, and fatigue and was diagnosed with N. meningitidis bacteremia. The causative strain was identified as serogroup W-135 ST-11 by polymerase chain reaction and multilocus sequence typing. Approximately 1 month after treatment, she developed high fever, dyspnea, chest pain, and shoulder pain due to pericarditis, polyarthritis, and tenosynovitis, which are all relatively common immunoreactive complications of W-135 ST-11 meningococcal infections. This causative strain was the same as that responsible for an outbreak of meningitis among Hajj pilgrims in 2000. The strain is now found worldwide because it can attain a high carriage rate and has a long duration of carriage. We suspect that our patient's infection was acquired from an imported chronic carrier.
影响因子：
3
作者：
Takahashi, H;Kuroki, T;Watanabe, H
通讯作者：
Watanabe, H