HNK-1-defined antigen detected in paraffin-embedded neuroectoderm tumors and those derived from cells of the amine precursor uptake and decarboxylation system.
HNK-1-defined antigen detected in paraffin-embedded neuroectoderm tumors and those derived from cells of the amine precursor uptake and decarboxylation system.
复制标题
在石蜡包埋的神经外胚层肿瘤以及源自胺前体摄取和脱羧系统的细胞中检测到的 HNK-1 定义的抗原。
作者:
J. Caillaud;S. Benjelloun;J. Bosq;K. Braham;M. Lipinski
The reactivity of the HNK-1 monoclonal antibody that, besides a subset of hematopoietic cells with natural killer activity, also detects neuroectodermal cells, was screened on 153 human tumors. Immunoperoxidase staining of paraffin sections revealed that HNK-1 detects neuroectoderm-derived cancers and tumors with endocrine activity. Because the antigen detected by HNK-1 is well conserved in paraffin sections, this antibody is of potential diagnostic value in routine histopathology and might help to elucidate the histogenesis of some poorly understood tumors.
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影响因子:
11.2
作者:
M. Herlyn;W. Clark;M. Mastrangelo;D. Guerry;D. Elder;D. Larossa;R. Hamilton;E. Bondi;R. Tuthill;Z. Steplewski;H. Koprowski
通讯作者:
M. Herlyn;W. Clark;M. Mastrangelo;D. Guerry;D. Elder;D. Larossa;R. Hamilton;E. Bondi;R. Tuthill;Z. Steplewski;H. Koprowski
影响因子:
11.2
作者:
Wikstrand,CJ;Bigner,DD
通讯作者:
Bigner,DD
DOI:
--
发表时间:
1981
期刊:
Journal of immunology (Baltimore, Md. : 1950)
影响因子:
--
作者:
Abo,T;Balch,CM
通讯作者:
Balch,CM
影响因子:
3.3
作者:
Trojanowski,JQ;Lee,VM
通讯作者:
Lee,VM
DOI:
10.1056/nejm198207153070305
发表时间:
1982-07
期刊:
The New England journal of medicine
影响因子:
--
作者:
J. Trojanowski;V. Lee;N. Pillsbury;S. Lee
通讯作者:
J. Trojanowski;V. Lee;N. Pillsbury;S. Lee