Effect of twisting on the behavior of a double-stranded polymer chain: A Monte Carlo simulation

Effect of twisting on the behavior of a double-stranded polymer chain: A Monte Carlo simulation
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扭曲对双链聚合物链行为的影响:蒙特卡罗模拟

DOI:
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发表时间:
1999
期刊:
影响因子:
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通讯作者:
A. Khokhlov
A. Khokhlov
中科院分区:
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文献类型:
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作者:
Y. Velichko;K. Yoshikawa;A. Khokhlov

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DNA和一些蛋白质具有多链结构,由于扭曲或各向异性刚性而表现出特有的三级结构。采用带键波动模型的蒙特卡罗模拟方法研究了链扭对环状双链聚合物链行为的影响。我们发现链式构象有两种形式,取决于它的扭曲程度。在第一种状态下,环链在弱扭的情况下表现为盘绕的线性链。在第二种状态下,链表现出以超卷曲结构为特征的尺度依赖性。
DNA and some proteins have a multistranded chain structure and exhibit characteristic tertiary structures due to twisting or anisotropic rigidity. We studied the effect of chain twisting on the behavior of a circular double-stranded polymer chain using a Monte Carlo simulation with bond fluctuation model. We found that there are two regimes for the chain conformation, depending on its twisting. In the first regime, with weak twisting, a circular chain behaves like a coiled linear chain. In the second regime, the chain shows scaling dependencies characterized by supercoiled structures.
DOI: 10.1006/jmbi.1994.1042
发表时间: 1994-01-21
影响因子: 5.6
作者:
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