Patient experience and anxiety during and after treatment for an HPV-related oropharyngeal cancer.
Patient experience and anxiety during and after treatment for an HPV-related oropharyngeal cancer.
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DOI：
10.1016/j.oraloncology.2016.06.009
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发表时间：
2016-09
期刊：
影响因子：
4.8
通讯作者：
Fakhry C
中科院分区：
文献类型：
--
作者：
D'Souza G;Zhang Y;Merritt S;Gold D;Robbins HA;Buckman V;Gerber J;Eisele DW;Ha P;Califano J;Fakhry C
HPV相关口咽癌的诊断包括独特的社会问题。然而，目前尚不清楚这些心理社会问题对患者有多常见，以及治疗后这些问题是否会继续存在。48例经病理证实的口咽癌患者(HPV-OPC，n=48)来自两个医学中心。参与者完成了一次电脑辅助的自我访谈，探索他们在治疗过程中和治疗后的心理社会经历。我们检查了总体上和按年龄划分的回答。大多数确诊为HPV-OPC的参与者报告说，他们被告知HPV可能(90%)或确实导致了他们的恶性肿瘤(77%)，但只有52%的人认为HPV是他们OPC的主要原因。65岁以上的参与者报告他们的医生告诉他们的肿瘤是HPV阳性的可能性低于年轻参与者(50%对84%，p=0.03)。他们的肿瘤与HPV相关的焦虑是参与者第一次诊断时的一个主要问题(93%)。然而，只有17%的人在治疗完成后仍报告有焦虑。虽然许多患者报告提供者充分讨论了诊断和治疗的情绪影响(58%)，但几乎一半的人报告说没有充分讨论这些情绪影响(24%)，或者根本没有讨论(18%)。此外，18%的人表示，他们的家人仍然对一些他们从未问过的问题感到疑惑。治疗后，一些HPV-OPC患者仍对HPV感到担忧，对HPV仍有疑问。年龄较大的患者对HPV在他们的癌症中的作用的认识较低。
Diagnosis with an HPV-related oropharyngeal cancer includes unique social issues. However, it is unknown how common these psychosocial issues are for patients and whether they continue after treatment. Patients with pathologically confirmed HPV-positive oropharyngeal cancer (HPV-OPC, n=48) were recruited from two medical centers. Participants completed a computer assisted self interview that explored their psychosocial experiences during and after treatment. We examined responses overall and by age. The majority of participants with confirmed HPV-OPC, reported being told that HPV could have (90%) or did cause (77%) their malignancy, but only 52% believed that HPV was the main cause of their OPC. Participants over 65 years were less likely than younger participants to report that their doctors told them their tumor was HPV-positive (50% vs 84%, p=0.03). Anxiety that their tumor was HPV-related was a major issue among participants when first diagnosed (93%). However, only 17% still reported anxiety after treatment was complete. While many patients reported that providers discussed the emotional effects of diagnosis and treatment adequately (58%), almost half reported discussing these emotional effects inadequately (24%), or not at all (18%). Further, 18% reported that their families still wondered about some questions that they had never asked. After treatment, some HPV-OPC patients remain concerned about HPV and have unanswered questions about HPV. Older patients had lower awareness of the role of HPV in their cancer.
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影响因子：
28.4
作者：
Rettig EM;Wentz A;Posner MR;Gross ND;Haddad RI;Gillison ML;Fakhry C;Quon H;Sikora AG;Stott WJ;Lorch JH;Gourin CG;Guo Y;Xiao W;Miles BA;Richmon JD;Andersen PE;Misiukiewicz KJ;Chung CH;Gerber JE;Rajan SD;D'Souza G
通讯作者：
D'Souza G
影响因子：
5.8
作者：
Chu, Amy;Genden, Eric;Sikora, Andrew
通讯作者：
Sikora, Andrew
影响因子：
3.5
作者：
Sparks, Lisa;Nussbaum, Jon F.
通讯作者：
Nussbaum, Jon F.
DOI：
10.1002/hed.23182
发表时间：
2013-11
影响因子：
2.9
作者：
Baxi, Shrujal S.;Shuman, Andrew G.;Corner, Geoffrey W.;Shuk, Elyse;Sherman, Eric J.;Elkin, Elena B.;Hay, Jennifer L.;Pfister, David G.
通讯作者：
Pfister, David G.
影响因子：
45.3
作者：
Gillison, Maura L.;Zhang, Qiang;Ang, K. Kian
通讯作者：
Ang, K. Kian