Acinetobacter baumannii infection in prior ICU bed occupants is an independent risk factor for subsequent cases of ventilator-associated pneumonia.
Acinetobacter baumannii infection in prior ICU bed occupants is an independent risk factor for subsequent cases of ventilator-associated pneumonia.
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DOI：
10.1155/2014/193516
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发表时间：
2014
影响因子：
--
通讯作者：
Zakynthinos E
中科院分区：
文献类型：
--
作者：
Tsakiridou E;Makris D;Daniil Z;Manoulakas E;Chatzipantazi V;Vlachos O;Xidopoulos G;Charalampidou O;Zakynthinos E
Objective. We aimed to evaluate risk factors for ventilator-associated pneumonia (VAP) due to Acinetobacter baumannii (AbVAP) in critically ill patients. Methods. This was a prospective observational study conducted in an intensive care unit (ICU) of a district hospital (6 beds). Consecutive patients were eligible for enrolment if they required mechanical ventilation for >48 hours and hospitalization for >72 hours. Clinical, microbiological, and laboratory parameters were assessed as risk factors for AbVAP by univariate and multivariate analysis. Results. 193 patients were included in the study. Overall, VAP incidence was 23.8% and AbVAP, 11.4%. Previous hospitalization of another patient with Acinetobacter baumannii infection was the only independent risk factor for AbVAP (OR (95% CI) 12.016 (2.282–19.521) P < 0.001). ICU stay (25 ± 17 versus 12 ± 9 P < 0.001), the incidence of other infections (OR (95% CI) 9.485 (1.640–10.466) P = 0.002) (urinary tract infection, catheter related infection, and bacteremia), or sepsis (OR (95% CI) 10.400 (3.749–10.466) P < 0.001) were significantly increased in patients with AbVAP compared to patients without VAP; no difference was found with respect to ICU mortality. Conclusion. ICU admission or the hospitalization of patients infected by Acinetobacter baumannii increases the risk of AbVAP by subsequent patients.
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影响因子：
4.9
作者：
Horan, Teresa C.;Andrus, Mary;Dudeck, Margaret A.
通讯作者：
Dudeck, Margaret A.
影响因子：
9.4
作者：
Chu, YW;Leung, CM;Cheng, AFB
通讯作者：
Cheng, AFB
影响因子：
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作者：
Mantzarlis K;Makris D;Manoulakas E;Karvouniaris M;Zakynthinos E
通讯作者：
Zakynthinos E
影响因子：
9.6
作者：
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通讯作者：
Rello, J
影响因子：
24.3
作者：
Rios, F. G.;Luna, C. M.;Apezteguia, C.
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Apezteguia, C.