Enhancement of psychotherapy using epigenetic modulating drugs.
Enhancement of psychotherapy using epigenetic modulating drugs.
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DOI：
10.1016/j.mehy.2011.03.042
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发表时间：
2011-07
影响因子：
4.7
通讯作者：
Sharma, Rajiv P.
中科院分区：
文献类型：
--
作者：
Gavin, David P.;Chase, Kayla A.;Sharma, Rajiv P.
Recent evidence suggests that covalent modifications to the genomic platform in the brain, that is DNA and its surrounding histones, provide a stable potentially lifelong mechanism for remembrance. Consequently, the making and unmaking of memories is accessible through pharmacological manipulations of these modifications. This has implications for psychotherapy and long-term rehabilitation of CNS disorders. We hypothesize that by enhancing learning through pharmacologically manipulating ‘epigenetic’ parameters, the effects of psychotherapies and rehabilitation can be enhanced.
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DOI：
10.1523/jneurosci.1758-09.2009
发表时间：
2009-09-16
期刊：
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子：
--
作者：
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通讯作者：
Nestler EJ
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影响因子：
25
作者：
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通讯作者：
Sweatt, J. David
DOI：
10.1523/jneurosci.4022-09.2010
发表时间：
2010-02-17
期刊：
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子：
--
作者：
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通讯作者：
Sheng M
影响因子：
5.5
作者：
HUBEL, DH;WIESEL, TN
通讯作者：
WIESEL, TN
DOI：
10.1124/jpet.107.120188
发表时间：
2007-06-01
影响因子：
3.5
作者：
Kim, Hyeon Ju;Rowe, Michael;Chuang, De-Maw
通讯作者：
Chuang, De-Maw