Advanced MR imaging of the placenta: Exploring the in utero placenta-brain connection.

Advanced MR imaging of the placenta: Exploring the in utero placenta-brain connection.
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DOI:
10.1053/j.semperi.2015.01.004
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发表时间:
2015-03
影响因子:
3.4
通讯作者:
Limperopoulos C
Limperopoulos C
中科院分区:
医学3区
文献类型:
--
作者:
Andescavage NN;du Plessis A;Limperopoulos C

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胎盘是胎儿健康神经发育所必需的重要器官。尽管胎盘功能障碍和神经功能障碍之间存在已知的相关性,但仍缺乏可靠评估体内胎盘健康和功能的工具。用于胎盘评估的现有临床工具在预测和评估胎盘健康方面仍然不敏感。先进的MRI技术为动态、非侵入性、实时评估胎盘健康和识别早期胎盘疾病提供了重要的前景。在这篇综述中,我们总结了胎盘评估的临床工具,包括超声,多普勒和常规MRI。然后,我们探讨了先进的胎盘磁共振成像技术的新兴作用,以支持胎儿的发展,评估定量MRI的优势和局限性,在识别胎盘功能障碍的早期标志物,改善妊娠监测和胎儿结局。
The placenta is a vital organ necessary for the healthy neurodevelopment of the fetus. Despite the known associations between placental dysfunction and neurologic impairment, there is a paucity of tools available to reliably assess in vivo placental health and function. Existing clinical tools for placental assessment remain insensitive in predicting and assessing placental well-being. Advanced MRI techniques hold significant promise for the dynamic, non-invasive, real-time assessment of placental health and identification of early placental-based disorders. In this review, we summarize the available clinical tools for placental assessment including ultrasound, Doppler, and conventional MRI. We then explore the emerging role of advanced placental MR imaging techniques for supporting the developing fetus, appraise the strengths and limitations of quantitative MRI in identifying early markers of placental dysfunction for improved pregnancy monitoring and fetal outcomes.
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