Advanced biomaterials for periodontal tissue regeneration.

Advanced biomaterials for periodontal tissue regeneration.
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DOI:
10.1002/dvg.23501
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发表时间:
2022-09
期刊:
Genesis (New York, N.Y. : 2000)
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其他
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牙周组织是再生干预的合适目标,因为它在疾病后不能在功能上恢复自身。重要的是,牙周组织有限的再生能力可以随着新型生物材料和治疗策略的发展而得到改善。值得注意的是,牙周组织的再生潜力不仅取决于其组织特异性结构和功能,还取决于其重建不同组织和组织界面的能力,这表明组织工程方法的进步最终可以为促进软硬牙周组织的组织重建提供新的视角。在这里,我们讨论了基于材料的生物活性线索,以及创新生物纤维技术的应用,以再生构成牙周组织的多种组织。
The periodontium is a suitable target for regenerative intervention, since it does not functionally restore itself after disease. Importantly, the limited regeneration capacity of the periodontium could be improved with the development of novel biomaterials and therapeutic strategies. Of note, the regenerative potential of the periodontium depends not only on its tissue‐specific architecture and function, but also on its ability to reconstruct distinct tissues and tissue interfaces, suggesting that the advancement of tissue engineering approaches can ultimately offer new perspectives to promote the organized reconstruction of soft and hard periodontal tissues. Here, we discuss material‐based, biologically active cues, and the application of innovative biofabrication technologies to regenerate the multiple tissues that comprise the periodontium.
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