MRI-based anatomical model of the human head for specific absorption rate mapping.

MRI-based anatomical model of the human head for specific absorption rate mapping.
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DOI:
10.1007/s11517-008-0414-z
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发表时间:
2008-12
影响因子:
3.2
通讯作者:
Bonmassar, Giorgio
Bonmassar, Giorgio
中科院分区:
工程技术3区
文献类型:
--
作者:
Makris, Nikos;Angelone, Leonardo;Tulloch, Seann;Sorg, Scott;Kaiser, Jonathan;Kennedy, David;Bonmassar, Giorgio

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在这项研究中,我们提出了一个磁共振成像(MRI)为基础的,高分辨率,数字模型的头部健康的人类受试者。为了制定模型,我们进行定量体积分割的人的头部,使用T1加权MRI。使用的高空间分辨率(1 × 1 × 1 mm 3)允许精确计算和可视化比以前模型提供的解剖结构数量更多的解剖结构。此外,高空间分辨率使我们能够研究目前在计算生物电磁学中采用的标准模型不可见的临床相关的单个薄解剖结构。当我们使用该高分辨率模型在7特斯拉MRI下计算电磁场和比吸收率(SAR)时,我们能够获得表皮/真皮、骨结构、骨髓、白色物质以及鼻和眼结构等精细解剖结构的详细可视化。
In this study, we present a magnetic resonance imaging (MRI)-based, high-resolution, numerical model of the head of a healthy human subject. In order to formulate the model, we performed quantitative volumetric segmentation on the human head, using T1-weighted MRI. The high spatial resolution used (1 × 1 × 1 mm3), allowed for the precise computation and visualization of a higher number of anatomical structures than provided by previous models. Furthermore, the high spatial resolution allowed us to study individual thin anatomical structures of clinical relevance not visible by the standard model currently adopted in computational bioelectromagnetics. When we computed the electromagnetic field and specific absorption rate (SAR) at 7 Tesla MRI using this high-resolution model, we were able to obtain a detailed visualization of such fine anatomical structures as the epidermis/dermis, bone structures, bone-marrow, white matter and nasal and eye structures.
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