MACSE v2: Toolkit for the Alignment of Coding Sequences Accounting for Frameshifts and Stop Codons.
MACSE v2: Toolkit for the Alignment of Coding Sequences Accounting for Frameshifts and Stop Codons.
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DOI:
10.1093/molbev/msy159
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发表时间:
2018-10-01
影响因子:
10.7
通讯作者:
Delsuc F
中科院分区:
文献类型:
--
作者:
Ranwez V;Douzery EJP;Cambon C;Chantret N;Delsuc F
Multiple sequence alignment is a prerequisite for many evolutionary analyses. Multiple Alignment of Coding Sequences (MACSE) is a multiple sequence alignment program that explicitly accounts for the underlying codon structure of protein-coding nucleotide sequences. Its unique characteristic allows building reliable codon alignments even in the presence of frameshifts. This facilitates downstream analyses such as selection pressure estimation based on the ratio of nonsynonymous to synonymous substitutions. Here, we present MACSE v2, a major update with an improved version of the initial algorithm enriched with a complete toolkit to handle multiple alignments of protein-coding sequences. A graphical interface now provides user-friendly access to the different subprograms.
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DOI:
10.1111/j.1471-8286.2007.01678.x
发表时间:
2007-05-01
期刊:
Molecular ecology notes
影响因子:
--
作者:
Ratnasingham S;Hebert PD
通讯作者:
Hebert PD
影响因子:
9.8
作者:
Machida RJ;Leray M;Ho SL;Knowlton N
通讯作者:
Knowlton N
影响因子:
3.4
作者:
Delsuc F;Gasse B;Sire JY
通讯作者:
Sire JY
影响因子:
2.8
作者:
Leray M;Yang JY;Meyer CP;Mills SC;Agudelo N;Ranwez V;Boehm JT;Machida RJ
通讯作者:
Machida RJ
影响因子:
3.7
作者:
Ranwez V;Harispe S;Delsuc F;Douzery EJ
通讯作者:
Douzery EJ