Structure of the HapX:CCAAT-binding protein complex with DNA: A piece of the puzzle revealed.

Structure of the HapX:CCAAT-binding protein complex with DNA: A piece of the puzzle revealed.
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DOI:
10.1016/j.str.2022.05.018
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发表时间:
2022-07-07
期刊:
影响因子:
5.7
通讯作者:
Moye-Rowley, W. Scott
Moye-Rowley, W. Scott
中科院分区:
生物学2区
文献类型:
--
作者:
Moye-Rowley, W. Scott

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来自曲霉属物种的HapX转录因子的DNA识别需要称为CCAAT结合复合物(CBC)的异源三聚体DNA结合蛋白的存在。在这一期的《结构》中,阐明CBC、HapX和DNA靶位点多价结合的结构基础。
DNA recognition by the HapX transcription factor from Aspergillus species requires the presence of a heterotrimeric DNA-binding protein called the CCAAT-binding complex (CBC). In this issue of Structure, illuminate the structural basis for the multivalent binding of the CBC, HapX and the DNA target site.
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