Synthesis and Glycosidation of Anomeric Halides: Evolution from Early Studies to Modern Methods of the 21st Century.
Synthesis and Glycosidation of Anomeric Halides: Evolution from Early Studies to Modern Methods of the 21st Century.
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DOI：
10.1021/acs.chemrev.2c00029
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发表时间：
2022-07-13
期刊：
影响因子：
62.1
通讯作者：
Demchenko, Alexei V.
中科院分区：
文献类型：
--
作者：
Singh, Yashapal;Geringer, Scott A.;Demchenko, Alexei V.
合成碳水化合物化学的进步极大地改善了获得普通聚糖的途径。然而，许多新方法仍然不能充分解决与化学糖基化和聚糖合成相关的挑战。由于糖基化的挑战仍然存在，科学家们经常回到传统的糖基供体。这篇综述致力于糖基卤化物，它们在塑造糖科学领域发挥了至关重要的作用，并继续为我们对化学糖基化的理解铺平道路。
Advances in synthetic carbohydrate chemistry have dramatically improved access to common glycans. However, many novel methods still fail to adequately address challenges associated with chemical glycosylation and glycan synthesis. Since a challenge of glycosylation has remained, scientists have been frequently returning to the traditional glycosyl donors. This review is dedicated to glycosyl halides that have played crucial roles in shaping the field of glycosciences and continue to pave the way toward our understanding of chemical glycosylation.
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影响因子：
62.1
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通讯作者：
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