Incidence of hypertension in a prospective cohort study of adults from Porto, Portugal.
Incidence of hypertension in a prospective cohort study of adults from Porto, Portugal.
复制标题
DOI：
10.1186/1471-2261-12-114
复制
发表时间：
2012-11-28
影响因子：
2.1
通讯作者：
Barros H
中科院分区：
文献类型：
--
作者：
Pereira M;Lunet N;Paulo C;Severo M;Azevedo A;Barros H
在过去的30年里，葡萄牙被描述为欧洲中位血压水平最高的国家之一，但高血压的发病率尚不清楚。本研究的目的是根据社会人口学特征和生活方式估计高血压的发病率。在1999-2003年（EPIPorto研究），从葡萄牙波尔图随机选择年龄≥18岁的居民组成一个基于人群的队列，在中位数3.8年后重新评估了796名无高血压的个体（62.6%为女性）。高血压定义为血压≥140/90 mmHg和/或接受降压药物治疗。使用Poisson回归估计发病率比（IRR）。总体发生率为47.3 [95%置信区间（95% CI）：40.5-55.5]/1000人-年。在女性中，发病率为43.4（35.6-53.1）/1000人-年，在男性中为52.7（41.3-68.0）/1000人-年。60岁以下女性的发病率较低，60岁以上女性的发病率高得多（男性为110.0 vs 64.4/1000人-年，年龄-性别相互作用p =0.032）。受高等教育的参与者患高血压的风险较低（≥13岁vs. ≤4岁：RR=0.70，95% CI，0.46-1.08，线性趋势p <0.001），与年龄和性别无关。超重和肥胖分别与高血压风险增加1.67倍和2.44倍相关，与年龄、性别和教育无关。在这个城市的葡萄牙人口高血压的发病率很高，新的病例主要发生在老年人，教育程度较低和超重肥胖。尽管最近在血压相关的结果方面取得了进展，但葡萄牙的高血压风险仍然高于其他发达国家。
During the past 30 years, Portugal has been described as one of the countries with highest median blood pressure levels in Europe, but the incidence of hypertension is unknown. The aim of this study was to estimate the incidence of hypertension, according to socio-demographic characteristics and lifestyles. A population-based cohort of randomly selected dwellers from Porto, Portugal, aged ≥18 years, was assembled in 1999–2003 (EPIPorto study) and 796 hypertension-free individuals (62.6% women) were reassessed after a median of 3.8 years. Hypertension was defined as blood pressure ≥140/90 mmHg and/or antihypertensive drug therapy. Incidence rate ratios (IRR) were estimated using Poisson regression. The overall incidence rate was 47.3 [95% confidence interval (95% CI): 40.5-55.5] per 1000 person-years. Among women, the incidence was 43.4 (35.6-53.1) and among men 52.7 (41.3-68.0) per 1000 person-years. The incidence was lower in women up to 60 years and much higher among women above 60 (110.0 vs. 64.4 per 1000 person-years among men, p for age-sex interaction=0.032). Participants with higher education had a lower risk of becoming hypertensive (≥13 years vs. ≤4 years: RR=0.70, 95% CI, 0.46-1.08, p for linear trend <0.001), independently of age and sex. Overweight and obesity were associated with a 1.67-fold and 2.44-fold increased risk of hypertension, respectively, independently of age, sex and education. In this urban Portuguese population the incidence rate of hypertension was high, with new cases occurring predominantly among older subjects, the less educated and those with overweight-obesity. Despite recent progresses in blood pressure related outcomes, the risk of hypertension remains higher in Portugal than in other developed countries.
登录
查看更多内容
影响因子：
5.6
作者：
Ramos, E;Lopes, C;Barros, H
通讯作者：
Barros, H
影响因子：
8.3
作者：
FORD, ES;COOPER, RS
通讯作者：
COOPER, RS
影响因子：
4.9
作者：
Gutierrez-Misis, Alicia;Sanchez-Santos, Maria T.;Otero, Angel
通讯作者：
Otero, Angel
影响因子：
4.9
作者：
Pimenta, Adriano M.;Beunza, Juan J.;Martinez-Gonzalez, Miguel A.
通讯作者：
Martinez-Gonzalez, Miguel A.
影响因子：
4.9
作者：
Mancia, Giuseppe;De Backer, Guy;Zanchetti, Alberto
通讯作者：
Zanchetti, Alberto