Measuring acute changes in adrenergic nerve activity of the heart in the living animal.
Measuring acute changes in adrenergic nerve activity of the heart in the living animal.
复制标题
测量活体动物心脏肾上腺素能神经活动的急性变化。
DOI:
10.1016/0002-8703(91)90671-4
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发表时间:
1991
影响因子:
4.8
通讯作者:
Johnson,J
中科院分区:
文献类型:
--
作者:
Sisson,JC;Bolgos,G;Johnson,J
Changes in the function of the adrenergic neurons of the heart may be important indicators of the adaptations of an animal to physiologic stress and disease. Rates of loss of norepinephrine (NE) from the heart were considered to be proportional to NE secretion and to adrenergic function. In rat hearts, yohimbine induced almost identical increases in rates of loss of3H-NE and of125I-metaiodobenzylguanidine (MIBG), a functional analog of NE. Clonidine induced decreases in rates of loss of3H-NE that were also mimicked by those of125I-MIBG. In the dog heart, pharmacologically-induced increases and decreases in rates of loss of123I-MIBG could be measured externally; these values were similar to those obtained for125I-MIBG in the rat heart. Thus acute changes in the adrenergic neuron activity can be measured in the living heart. The method is applicable to man in determining the capacity of the adrenergic system to respond to provocative challenges.
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影响因子:
3.3
作者:
ELMANSHAWI, A;KILLIAN, KJ;JONES, NL
通讯作者:
JONES, NL
DOI:
10.1152/jappl.1983.55.6.1932
发表时间:
1983
期刊:
Journal of applied physiology: respiratory, environmental and exercise physiology
影响因子:
--
作者:
Leith,DE
通讯作者:
Leith,DE
DOI:
--
发表时间:
1968
期刊:
Respiration Physiology
影响因子:
--
作者:
J. Remmers;J. E. Brooks;S. Tenney
通讯作者:
S. Tenney
DOI:
10.1152/jappl.1981.51.6.1471
发表时间:
1981
期刊:
Journal of applied physiology: respiratory, environmental and exercise physiology
影响因子:
--
作者:
Strohl,KP;Mead,J;Banzett,RB;Loring,SH;Kosch,PC
通讯作者:
Kosch,PC
影响因子:
6.7
作者:
E. Campbell;J. Howell
通讯作者:
J. Howell