Rhythmic TMS over parietal cortex links distinct brain frequencies to global versus local visual processing.

Rhythmic TMS over parietal cortex links distinct brain frequencies to global versus local visual processing.
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DOI:
10.1016/j.cub.2011.01.035
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发表时间:
2011-02-22
期刊:
影响因子:
9.2
通讯作者:
Thut, Gregor
Thut, Gregor
中科院分区:
生物学1区
文献类型:
--
作者:
Romei, Vincenzo;Driver, Jon;Schyns, Philippe G.;Thut, Gregor

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视觉感知的神经网络在不同的频率下表现出振荡(例如,)。但这些如何映射到视觉感知的不同方面仍然难以捉摸。最近的脑电图数据表明,当意识知觉分别被可逆性视觉刺激的整体或局部特征所主导时,顶叶传感器的θ或β频率的振幅会增加。但这只提供了相关的、非干预性的证据。在这里,我们通过经颅磁刺激(TMS)干预表明,在θ或β频率下,右顶叶经颅磁刺激的短节奏爆发可以分别对分层视觉刺激的整体或局部水平的加工产生影响,特别是在显著不一致干扰物的背景下。这种θ波和β波经颅磁刺激之间的双重分离揭示了特定频率在处理全局和局部视觉特征方面的独特因果作用。节奏性经颅磁刺激以特定频率的方式针对特定的大脑过程►β频率的右脑顶叶经颅磁刺激选择性地增强局部视觉处理►theta频率的右脑顶叶经颅磁刺激选择性地增强整体视觉处理►节奏性经颅磁刺激是一种针对特定频率的大脑功能干预的有力工具
Neural networks underlying visual perception exhibit oscillations at different frequencies (e.g.,). But how these map onto distinct aspects of visual perception remains elusive. Recent electroencephalography data indicate that theta or beta frequencies at parietal sensors increase in amplitude when conscious perception is dominated by global or local features, respectively, of a reversible visual stimulus. But this provides only correlative, noninterventional evidence. Here we show via transcranial magnetic stimulation (TMS) interventions that short rhythmic bursts of right-parietal TMS at theta or beta frequency can causally benefit processing of global or local levels, respectively, for hierarchical visual stimuli, especially in the context of salient incongruent distractors. This double dissociation between theta and beta TMS reveals distinct causal roles for particular frequencies in processing global versus local visual features. ► Rhythmic TMS causally targets particular brain processes in a frequency-specific way ► Right-parietal TMS at beta-frequency selectively enhances local visual processing ► Right-parietal TMS at theta-frequency selectively enhances global visual processing ► Rhythmic TMS is a powerful tool for frequency-specific interventions in brain function
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