Recurrent Dermatofibrosarcoma Protuberans with Myxoid and Fibrosarcomatous Changes Paralleled by Loss of CD34 Expression
Recurrent Dermatofibrosarcoma Protuberans with Myxoid and Fibrosarcomatous Changes Paralleled by Loss of CD34 Expression
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复发性隆起性皮肤纤维肉瘤伴有粘液样和纤维肉瘤变化，同时伴有 CD34 表达缺失
DOI：
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发表时间：
1995
期刊：
影响因子：
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通讯作者：
Yasushi Tomita
中科院分区：
文献类型：
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作者：
N. Sato;K. Kimura;Yasushi Tomita
一名38岁女性主诉其前胸壁复发性结节。她在12岁时发现了第一个结节，此后共接受了31次手术切除。最后，需要广泛切除部分肋软骨和胸骨，并重建胸壁。对一系列手术标本的组织学检查进行了重新评估。通过抗CD 34抗体对肿瘤进行免疫组织化学染色，明确诊断为隆突性皮肤纤维肉瘤（DFSP）。一个值得注意的结果是，她的DFSP并不总是表达CD 34;粘液样和纤维肉瘤样变化的复发肿瘤失去了CD 34的表达。
A 38‐year‐old woman complained of recurrent nodules on her anterior chest wall. She noticed the first nodule at the age of 12 and has since undergone surgical removal a total of 31 times. Finally, wide resection of parts of the rib cartilage and sternum and chest wall reconstruction were required. Histopathological examination of a series of surgical specimens were reevaluated. Immunohistochemical staining of the tumors by anti‐CD34 antibody provided a definite diagnosis of dermatofibrosarcoma protuberans (DFSP). A noteworthy result was that her DFSP did not always express CD34; the recurrent tumors with myxoid and fibrosarcomatous changes lost their CD34 expression.
影响因子：
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作者：
B. Nickoloff
通讯作者：
B. Nickoloff