The Effect of Diesel Fuel Reformulation on the Exhaust Measured by Ames Mutagenicity and DNA AddUcts

The Effect of Diesel Fuel Reformulation on the Exhaust Measured by Ames Mutagenicity and DNA AddUcts
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通过 Ames 致突变性和 DNA 加合物测量柴油重新配制对尾气的影响

DOI:
10.1080/03067310290024139
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发表时间:
2002
影响因子:
2.6
通讯作者:
K. Savela
K. Savela
中科院分区:
化学4区
文献类型:
--
作者:
S. Isotalo;T. Kuljukka;L. Rantanen;S. Mikkonen;K. Savela

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In this study we compared two reformulated and one standard European Diesel fuel between particulate soluble organic fraction of PAH, mutagenic activity, and DNA adduct formation. Adducts were analyzed in vitro calf thymus DNA with and without the metabolic activation system and measured by 32 P-postlabeling method. PAH-DNA adduct formation and mutagenicity by Ames test were compared. Both biological tests showed that reformulation decreased genotoxic PAH compounds in diesel particle emission.
DOI: 10.1016/s0165-1218(96)90103-2
发表时间: 1996-12-20
期刊: MUTATION RESEARCH-GENETIC TOXICOLOGY
影响因子: --
作者:
Durant, JL;Busby, WF;Crespi, CL
通讯作者: Crespi, CL