EVOLUTIONARY DYNAMICS OF A SPATIALLY STRUCTURED HOST-PARASITE ASSOCIATION: DROSOPHILA INNUBILA AND MALE-KILLING WOLBACHIA
EVOLUTIONARY DYNAMICS OF A SPATIALLY STRUCTURED HOST-PARASITE ASSOCIATION: DROSOPHILA INNUBILA AND MALE-KILLING WOLBACHIA
复制标题
空间结构的宿主-寄生虫关联的进化动力学：果蝇 Innubila 和雄性杀伤性沃尔巴克虫 (Wolbachia)
DOI：
10.1111/j.0014-3820.2005.tb01801.x
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发表时间：
2005
期刊：
影响因子：
3.5
通讯作者：
J. Jaenike
中科院分区：
文献类型：
--
作者：
K. Dyer;J. Jaenike
寄主-寄生虫进化的方式和节奏取决于种群结构和历史，以及物种之间相互作用的选择强度。在这里，我们对食霉性果蝇及其杀死雄性的沃尔巴克氏菌内共生菌的种群进行遗传学和流行病学特征分析，目的是通过这种联系的全球性将当地整合起来。影射果蝇生活在美国西南部和墨西哥北部森林覆盖的“天空岛”地区，在那里它的分布高度分散。我们研究了地理上孤立的星形吸虫天空岛种群，调查了沃尔巴克氏菌感染的频率和表达，以及宿主和寄生虫种群内和种群之间的遗传变异分布。在所有种群中，沃尔巴克氏菌感染与几乎完全杀死男性有关，因此没有证据表明种群特有的相互作用表型或局部耐药性的演变。虽然各主要种群都存在沃尔巴克氏菌感染，但各种群之间的感染率和由此产生的种群水平性别比存在差异。在这些种群中，金线虫的核基因表现出中等但显著的分化。相比之下，宿主线粒体DNA(MtDNA)与沃尔巴克氏菌共享传播，即使在考虑核基因和线粒体基因之间的传播差异后，也表现出更大的地理分化。我们认为这种模式是由局部的沃尔巴克氏菌引起的，而不是由D innubila引起的，这种波动增加了只由mtDNA经历的漂移的严重性。总体而言，我们的数据表明，在当地种群中，金黄色葡萄球菌和杀死雄性的沃尔巴克氏菌之间的联系是生态动态的，但在整个物种中，进化上是一致的。
Abstract The mode and tempo of host-parasite evolution depend on population structure and history and the strength of selection that the species exert on each other. Here we genetically and epidemiologically characterize populations of the mycophagous fly Drosophila innubila and its male-killing Wolbachia endosymbiont, with the aim of integrating the local through global nature of this association. Drosophila innubila inhabit the forested “sky island” regions of the of the southwestern United States and northern Mexico, where its distribution is highly fragmented. We examine geographically isolated sky island populations of D. innubila, surveying the frequency and expression of Wolbachia infection as well as the distribution of genetic variation within and among populations of the host and parasite. In all populations, Wolbachia infection is associated with virtually complete male-killing, thus providing no evidence for the evolution of population-specific interaction phenotypes or local resistance. Although Wolbachia infection occurs in each of the main populations, there is variation among populations in the prevalence of infection and the resulting population-level sex ratio of D. innubila. Among these populations, the nuclear genes of D. innubila show moderate, though significant, differentiation. In contrast, the host mitochondrial DNA (mtDNA), which shares transmission with Wolbachia, exhibits substantially greater geographic differentiation, even after accounting for differences in transmission between nuclear and mitochondrial genes. We suggest that this pattern is caused by local Wolbachia—but not D. innubila—fluctuations in prevalence that increase the severity of drift experienced only by the mtDNA. Overall, our data suggest that the association between D. innubila and male-killing Wolbachia is ecologically dynamic within local populations, but evolutionarily coherent across the species as a whole.
影响因子：
10.7
作者：
M. Lynch;T. Crease
通讯作者：
M. Lynch;T. Crease
影响因子：
10.7
作者：
R. Hudson;D. Boos;N. Kaplan
通讯作者：
R. Hudson;D. Boos;N. Kaplan
影响因子：
9.8
作者：
Stephens, M;Donnelly, P
通讯作者：
Donnelly, P