Genetic Diversity, Recombination, and Divergence in Animal Associated Penicillium dipodomyis
Genetic Diversity, Recombination, and Divergence in Animal Associated Penicillium dipodomyis
复制标题
动物相关青霉的遗传多样性、重组和分化
作者：
Daniel A Henk;M. Fisher
Penicillium dipodomyis 被认为是一种与袋鼠、Dipodomys 物种相关的独特无性真菌，并且在青霉属物种中是独一无二的，它可以在 37°C 下生长，但不产生已知的毒素。 P. dipodomyis 内缺乏重组将导致有限的适应性灵活性，但可能通过维持有利的基因型来增强局部适应和宿主选择。在这里，对来自五个蛋白质编码基因的 DNA 序列数据的分析表明，重组发生在 P. dipodomyis 内的小空间尺度上。此外，交配型等位基因的检测支持了 P. dipodomyis 的异型杂交和性周期。在体外试验中，与与袋鼠相关的其他青霉属物种相比，P. dipodomyis 是较弱的竞争者。贝叶斯物种水平分析表明，P. dipodomyis 谱系与约 1100 万年前在袋鼠鼠颊囊及其储存的种子中发现的密切相关物种分化，与 Dipodomys 与其姐妹啮齿动物类群的分化时间相似。
Penicillium dipodomyis is thought to be an exclusively asexual fungus associated with Kangaroo Rats, Dipodomys species, and is unique among Penicillium species in growing at 37°C but producing no known toxins. Lack of recombination within P. dipodomyis would result in limited adaptive flexibility but possibly enhance local adaptation and host selection via maintenance of favourable genotypes. Here, analysis of DNA sequence data from five protein-coding genes shows that recombination occurs within P. dipodomyis on a small spatial scale. Furthermore, detection of mating-type alleles supports outcrossing and a sexual cycle in P. dipodomyis. P. dipodomyis was a weaker competitor in in vitro assays with other Penicillium species found in association with Kanagaroo rats. Bayesian species level analysis suggests that the P. dipodomyis lineage diverged from closely related species also found in cheek pouches of Kangaroo Rats and their stored seeds about 11 million years ago, a similar divergence time as Dipodomys from its sister rodent taxa.
影响因子：
6
作者：
Heitman, Joseph
通讯作者：
Heitman, Joseph