Solvent‐Free Aqueous Dispersions of Block Copolyesters for Electrospinning of Biodegradable Nonwoven Mats for Biomedical Applications
Solvent‐Free Aqueous Dispersions of Block Copolyesters for Electrospinning of Biodegradable Nonwoven Mats for Biomedical Applications
复制标题
用于生物医学应用的可生物降解非织造垫静电纺丝的嵌段共聚酯无溶剂水分散体
DOI：
10.1002/mame.201400116
复制
发表时间：
2014
影响因子：
3.9
通讯作者：
A. Greiner
中科院分区：
文献类型：
--
作者：
K. Bubel;D. Grunenberg;G. Vasilyev;E. Zussman;S. Agarwal;A. Greiner
生物可降解嵌段共聚酯是在不使用任何有机溶剂的情况下从水中加工成水稳定的电纺纤维的，这在各种应用中具有重要的意义。共聚酯(ϵ-己内酯-b-甲氧基聚乙二醇酯)(PCL-b-mEg)在90 °C的水中，在聚氧乙烯(PEO)存在下，采用熔融分散的方法进行乳化。在共聚酯水分散体中加入PEO后，粘度显著增加。利用流变学研究证明了PCL-b-mpeg/PEO水分散体中结构形成的证据。通过静电纺丝，制得了PCL嵌段长度相关的水性稳定纳米纤维非织造布。
Biodegradable block copolyesters are processed from water to water-stable electrospun fibers without use of any organic solvent, which is of major importance for a variety of applications. The copolyesters (poly(ϵ-caprolactone-b-methoxypolyethylene glycol)) (PCL-b-MPEG)) are emulsified in water at 90 °C in presence of poly(ethylene oxide) (PEO) using melt dispersion method. Dramatic increase in viscosity is observed upon addition of PEO to aqueous dispersions of copolyesters. Evidence of structure formation in aqueous PCL-b-MPEG/PEO dispersions is adduced using rheological studies. PCL block length dependent water stable nanofiber non-wovens are obtained upon electrospinning of the dispersions.
影响因子：
6.7
作者：
Xie, Jingwei;MacEwan, Matthew R.;Xia, Younan
通讯作者：
Xia, Younan