Reading Front to Back: MEG Evidence for Early Feedback Effects During Word Recognition
Reading Front to Back: MEG Evidence for Early Feedback Effects During Word Recognition
复制标题
从头到尾阅读：MEG 证据证明单词识别过程中的早期反馈效应
作者：
Zoe V. J. Woodhead;Gareth R. Barnes;William D. Penny;R. J. Moran;Sundeep Teki;Sundeep Teki;Cathy J. Price;Alexander P. Leff
人类脑磁图研究显示，在单词呈现后约130 ms，左额下回（IFG）出现单词选择性活动（Pammer et al. 2004; Cornelissen et al. 2009; Wheat et al. 2010）。这种早期额叶反应的作用目前尚不清楚。我们测试的假设，IFG提供了自上而下的限制词识别使用动态因果模型收集的脑磁图数据，而受试者看到的书面文字和虚假的字体刺激。使用变分贝叶斯等效电流偶极子源重建确定了左枕叶和右枕叶、腹侧枕颞叶和额叶皮质中的受试者特定偶极子。连通性分析测试如何字和假字体刺激差异调制这些区域之间的活动在刺激后的第一个300毫秒。我们发现，左下额叶活动表现出更强的敏感性字比假字体和更强的反馈连接到左腹侧枕颞叶皮层（vOT）在第一个200毫秒。随后，观察到的影响，相对于假字体的话，从左枕向腹侧枕颞和额叶区域的前馈连接。这些研究结果表明，左下额叶活动调制vOT在早期阶段的文字处理，并提供了一个机械帐户的自上而下的影响，在文字识别。
Magnetoencephalography studies in humans have shown word-selective activity in the left inferior frontal gyrus (IFG) approximately 130 ms after word presentation ( Pammer et al. 2004; Cornelissen et al. 2009; Wheat et al. 2010). The role of this early frontal response is currently not known. We tested the hypothesis that the IFG provides top-down constraints on word recognition using dynamic causal modeling of magnetoencephalography data collected, while subjects viewed written words and false font stimuli. Subject-specific dipoles in left and right occipital, ventral occipitotemporal and frontal cortices were identified using Variational Bayesian Equivalent Current Dipole source reconstruction. A connectivity analysis tested how words and false font stimuli differentially modulated activity between these regions within the first 300 ms after stimulus presentation. We found that left inferior frontal activity showed stronger sensitivity to words than false font and a stronger feedback connection onto the left ventral occipitotemporal cortex (vOT) in the first 200 ms. Subsequently, the effect of words relative to false font was observed on feedforward connections from left occipital to ventral occipitotemporal and frontal regions. These findings demonstrate that left inferior frontal activity modulates vOT in the early stages of word processing and provides a mechanistic account of top-down effects during word recognition.
影响因子：
3.7
作者：
Felleman, Daniel J.;Van Essen, David C.
通讯作者：
Van Essen, David C.
DOI：
10.1037//0096-1523.24.3.767
发表时间：
1998-06
期刊：
Journal of experimental psychology. Human perception and performance
影响因子：
--
作者：
Manuel Perea;Manuel Perea;A. Pollatsek
通讯作者：
Manuel Perea;Manuel Perea;A. Pollatsek