Mitochondrial replacement therapies can circumvent mtDNA-based disease transmission.
Mitochondrial replacement therapies can circumvent mtDNA-based disease transmission.
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DOI:
10.1016/j.cmet.2014.06.012
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发表时间:
2014-07-01
期刊:
影响因子:
29
通讯作者:
Mitalipov S
中科院分区:
文献类型:
--
作者:
Wolf DP;Mitalipov S
Mitochondrial DNA diseases are relatively common, sometimes devastating and transmitted exclusively through the egg to children of carrier mothers. The study by Wang et al. (2014) adds the exciting possibility of a new therapy for preventing mitochondrial disease transmission predicated on the use of polar body genomes in mice. Mitochondrial DNA diseases are relatively common, sometimes devastating and transmitted exclusively through the egg to children of carrier mothers. The study by Wang et al. (2014) adds the exciting possibility of a new therapy for preventing mitochondrial disease transmission predicated on the use of polar body genomesin mice.
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影响因子:
8.8
作者:
Lee HS;Ma H;Juanes RC;Tachibana M;Sparman M;Woodward J;Ramsey C;Xu J;Kang EJ;Amato P;Mair G;Steinborn R;Mitalipov S
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影响因子:
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