Vestibulo-ocular reflex (VOR) preserved in bilateral severe vestibular malformations with internal auditory canal stenosis

Vestibulo-ocular reflex (VOR) preserved in bilateral severe vestibular malformations with internal auditory canal stenosis
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双侧严重前庭畸形伴内耳道狭窄时保留前庭眼反射 (VOR)

DOI:
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发表时间:
2007
影响因子:
1.4
通讯作者:
Masako Nakamura
Masako Nakamura
中科院分区:
医学4区
文献类型:
--
作者:
Mitsuya Suzuki;Yu Saito;M. Ushio;T. Yamasoba;Izumi Hatta;Masako Nakamura

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一位60岁的双侧耳聋患者来到我们的门诊。计算机断层扫描(CT)显示内耳畸形,包括耳蜗发育不全,右耳前庭发育不全,左耳共有腔,内耳道狭窄。我们采用热刺激和地垂直轴旋转(EVAR)或离垂直轴旋转(OVAR)刺激进行眼震电图,并研究了前庭诱发肌源电位(VEMPs)和前庭眼反射(VOR)。轻度水平眼震是由EVAR刺激引起的,而不是由热量刺激引起的。在OVAR期间观察到轻微的垂直眼震,而VEMP试验没有引起反应。在黑暗中进行水平或垂直VOR的结果几乎正常。这些结果表明,即使内耳严重畸形,双侧迷路功能明显降低,直到旋转刺激轻微引起眼球震颤,也可以获得VOR。
A 60-year-old woman, who has suffered from bilateral deafness throughout her life, visited our outpatient clinic. Computed tomography (CT) revealed inner ear malformations, which comprise cochlear aplasia with hypoplastic vestibule in the right ear and a common cavity in the left ear, and narrow internal auditory canals. We performed electronystagmography with caloric stimulation and stimulation of earth-vertical axis rotation (EVAR) or off-vertical axis rotation (OVAR), and studied vestibular evoked myogenic potentials (VEMPs) and vestibular ocular reflex (VOR). Slight horizontal nystagmus was induced by the stimulation of EVAR but not by caloric stimulation. Slight vertical nystagmus was observed during OVAR, whereas the VEMP test elicited no response. The result of horizontal or vertical VOR performed in the dark was almost normal. These findings suggest that VOR can be acquired even with severe malformation of the inner ear whose labyrinthine functions markedly reduce bilaterally until nystagmus is slightly induced by rotation stimulation.
DOI: 10.1152/jn.2001.85.3.1119
发表时间: 2001
期刊: Journal of neurophysiology.
影响因子: --
作者:
Goode,CT;Maney,DL;Rubel,EW;Fuchs,AF
通讯作者: Fuchs,AF