Transcriptome sequencing of melanocytic nevi and melanomas from Grm1 transgenic mice to determine melanoma driver mutations
Transcriptome sequencing of melanocytic nevi and melanomas from Grm1 transgenic mice to determine melanoma driver mutations
复制标题
对 Grm1 转基因小鼠的黑素细胞痣和黑色素瘤进行转录组测序以确定黑色素瘤驱动突变
DOI:
10.1111/pcmr.12244
复制
发表时间:
2014
影响因子:
4.3
通讯作者:
Bosserhoff AK
中科院分区:
文献类型:
--
作者:
de Jel MM;Engelmann JC;Kunz M;Schiffner S;Kuphal S;Bosserhoff AK
The article discusses a study done to determine melanoma driver mutations using transcriptome sequencing of melanocytic nevi and melanomas from Grm1 transgenic mice. Topics discussed include high base mutation rate of malignant melanoma, importance of understanding the role of mutations in melanoma development, and identification of chromosomal positions with somatic alterations.
影响因子:
4.8
作者:
Gooch, JL;Christy, B;Yee, D
通讯作者:
Yee, D
影响因子:
3.6
作者:
Schiffner, Susanne;Chen, Suzie;Bosserhoff, Anja-Katrin
通讯作者:
Bosserhoff, Anja-Katrin