Organization of the genes encoding complement receptors type 1 and 2, decay-accelerating factor, and C4-binding protein in the RCA locus on human chromosome 1
Organization of the genes encoding complement receptors type 1 and 2, decay-accelerating factor, and C4-binding protein in the RCA locus on human chromosome 1
复制标题
人类 1 号染色体 RCA 基因座中编码补体受体 1 型和 2 型、衰变加速因子和 C4 结合蛋白的基因的组织
DOI:
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发表时间:
1988
影响因子:
15.3
通讯作者:
D. T. Fearon
中科院分区:
文献类型:
--
作者:
Michael C. Carroll;E. Alicot;Philip J. Katzman;L B Klickstein;John A. Smith;D. T. Fearon
The organization and physical linkage of four members of a major complement locus, the RCA locus, have been determined using the technique of pulsed field gradient gel electrophoresis in conjunction with Southern blotting. The genes encoding CR1, CR2, DAF, and C4bp were aligned in that order within a region of 750 kb. In addition, the 5' to 3' orientation of the CR1 gene (5' proximal to CR2) was determined using 5'- and 3'-specific DNA probes. The proximity of these genes may be related to structural and functional homologies of the protein products. Overall, a restriction map including 1,500 kb of DNA was prepared, and this map will be important for positioning of additional coding sequences within this region on the long arm of chromosome 1.
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DOI:
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发表时间:
1985
期刊:
Journal of immunology (Baltimore, Md. : 1950)
影响因子:
--
作者:
Wong,WW;Fearon,DT
通讯作者:
Fearon,DT
影响因子:
4.4
作者:
A. Nicholson‐Weller;J. Burge;D. Fearon;P. Weller;K. Austen
通讯作者:
A. Nicholson‐Weller;J. Burge;D. Fearon;P. Weller;K. Austen
影响因子:
4.4
作者:
J. Weis;C. Morton;G. Bruns;J. Weis;L. Klickstein;W. Wong;D. Fearon
通讯作者:
J. Weis;C. Morton;G. Bruns;J. Weis;L. Klickstein;W. Wong;D. Fearon
DOI:
10.1073/pnas.83.15.5639
发表时间:
1986
影响因子:
11.1
作者:
Weis,JJ;Fearon,DT;Klickstein,LB;Wong,WW;Richards,SA;deBruynKops,A;Smith,JA;Weis,JH
通讯作者:
Weis,JH
DOI:
10.1073/pnas.81.24.7890
发表时间:
1984
影响因子:
11.1
作者:
RodriguezdeCordoba,S;Dykman,TR;Ginsberg-Fellner,F;Ercilla,G;Aqua,M;Atkinson,JP;Rubinstein,P
通讯作者:
Rubinstein,P