Khat use is associated with impaired working memory and cognitive flexibility.
Khat use is associated with impaired working memory and cognitive flexibility.
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KHAT的使用与工作记忆和认知灵活性受损有关。
DOI：
10.1371/journal.pone.0020602
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发表时间：
2011
期刊：
影响因子：
3.7
通讯作者：
Hommel B
中科院分区：
文献类型：
--
作者：
Colzato LS;Ruiz MJ;van den Wildenberg WP;Hommel B
过去几十年来，阿拉伯茶的消费在东非有所增加，并已成为一种全球现象，蔓延到世界其他地区的族裔社区，如荷兰、联合王国、加拿大和美国。然而，人们对阿茶使用者使用阿茶与认知控制功能之间的关系知之甚少。我们研究了阿拉伯茶的使用是否与工作记忆（WM）和认知灵活性，两个中央认知控制功能的变化。阿拉伯茶使用者和无阿拉伯茶对照组在性别、种族、年龄、酒精和大麻消费以及智商（Raven渐进矩阵）方面相匹配。小组进行了测试的认知灵活性，作为衡量的全球本地任务，并在WM使用N-回任务。阿拉伯茶用户的表现显着比控制任务挖掘到认知灵活性，以及在WM的信息监测。目前的研究结果表明，阿拉伯茶使用损害认知灵活性和更新的信息在WM。无法监控WM中的信息并快速灵活地调整行为可能会对日常生活活动产生影响。
Khat consumption has increased during the last decades in Eastern Africa and has become a global phenomenon spreading to ethnic communities in the rest of the world, such as The Netherlands, United Kingdom, Canada, and the United States. Very little is known, however, about the relation between khat use and cognitive control functions in khat users. We studied whether khat use is associated with changes in working memory (WM) and cognitive flexibility, two central cognitive control functions. Khat users and khat-free controls were matched in terms of sex, ethnicity, age, alcohol and cannabis consumption, and IQ (Raven's progressive matrices). Groups were tested on cognitive flexibility, as measured by a Global-Local task, and on WM using an N-back task. Khat users performed significantly worse than controls on tasks tapping into cognitive flexibility as well as monitoring of information in WM. The present findings suggest that khat use impairs both cognitive flexibility and the updating of information in WM. The inability to monitor information in WM and to adjust behavior rapidly and flexibly may have repercussions for daily life activities.
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影响因子：
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