Motor modulation of afferent somatosensory circuits.

Motor modulation of afferent somatosensory circuits.
复制标题

DOI:
10.1038/nn.2227
复制
发表时间:
2008-12
影响因子:
25
通讯作者:
Simons, Daniel J.
Simons, Daniel J.
中科院分区:
医学1区
文献类型:
--
作者:
Lee, SooHyun;Carvell, George E.;Simons, Daniel J.

文献摘要

参考文献

被引文献

相似文献

感觉系统中丘脑皮质回路的一个显着特征是从皮质到丘脑神经元的广泛且高度组织的反馈投射,为皮质提供刺激特异性输入。在轻度镇静的大鼠中,我们发现运动皮层活动的局部增强促进了初级体感皮层中拓扑排列的神经元的感觉诱发反应,包括逆向识别的皮质丘脑细胞;在腹侧后内侧丘脑 (VPm) 中观察到类似的效果。在行为正常的大鼠中,丘脑反应通常在搅拌过程中较小,但当脑干三叉神经核中的信号传递被绕过或改变时较大。在随意运动期间,脑干中的感觉活动可能受到全局抑制,而皮质促进的 VPm 神经元的信号传导相对于未接受此类促进的其他 VPm 神经元同时增强。
A prominent feature of thalamocortical circuitry in sensory systems is the extensive and highly organized feedback projection from the cortex to the thalamic neurons that provide stimulus-specific input to the cortex. In lightly sedated rats, we found that focal enhancement of motor cortex activity facilitated sensory-evoked responses of topographically aligned neurons in primary somatosensory cortex, including antidromically identified corticothalamic cells; similar effects were observed in ventral posterior medial thalamus (VPm). In behaving rats, thalamic responses were normally smaller during whisking but larger when signal transmission in brainstem trigeminal nuclei was bypassed or altered. During voluntary movement, sensory activity may be globally suppressed in the brainstem, whereas signaling by cortically facilitated VPm neurons is simultaneously enhanced relative to other VPm neurons receiving no such facilitation.
DOI: 10.1093/cercor/13.1.53
发表时间: 2003-01-01
期刊: CEREBRAL CORTEX
影响因子: 3.7
作者:
Ahissar, E;Kleinfeld, D
通讯作者: Kleinfeld, D
DOI: 10.1016/j.neuron.2007.10.007
发表时间: 2007-12-06
期刊: NEURON
影响因子: 16.2
作者:
Ferezou, Isabelle;Haiss, Florent;Petersen, Carl C. H.
通讯作者: Petersen, Carl C. H.
DOI: 10.1093/cercor/bhj056
发表时间: 2006-08-01
期刊: CEREBRAL CORTEX
影响因子: 3.7
作者:
Hentschke, Harald;Haiss, Florent;Schwarz, Cornelius
通讯作者: Schwarz, Cornelius
DOI: 10.1523/jneurosci.3760-04.2005
发表时间: 2005-02-09
影响因子: 5.3
作者:
Haiss, F;Schwarz, C
通讯作者: Schwarz, C
DOI: 10.1152/jn.1974.37.5.831
发表时间: 1974-01-01
影响因子: 2.5
作者:
COULTER, JD
通讯作者: COULTER, JD