Quantitative T2-Mapping and T2(⁎)-Mapping Evaluation of Changes in Cartilage Matrix after Acute Anterior Cruciate Ligament Rupture and the Correlation between the Results of Both Methods.
Quantitative T2-Mapping and T2(⁎)-Mapping Evaluation of Changes in Cartilage Matrix after Acute Anterior Cruciate Ligament Rupture and the Correlation between the Results of Both Methods.
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定量T2-Mapping和T2-Mapping评估急性前十字韧带断裂后软骨基质的变化以及两种方法结果之间的相关性
DOI：
10.1155/2018/7985672
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发表时间：
2018
影响因子：
--
通讯作者：
Chen S
中科院分区：
文献类型：
--
作者：
Tao H;Qiao Y;Hu Y;Xie Y;Lu R;Yan X;Chen S
应用T2和T2磁共振成像技术定量评价急性前交叉韧带（ACL）断裂后软骨基质的变化，并分析两种方法结果之间的相关性。 23例患者和23名健康对照者入选并接受定量MRI检查。将膝关节软骨分为6个部分，包括股骨外侧（LF）、胫骨外侧（LT）、股骨内侧（MF）、胫骨内侧（MT）、胫骨托（Tr）和髌骨（Pa）。T2和T2 Δ值在全层以及每个软骨隔室的浅层和深层中测量。采用非配对Student t检验比较患者与对照组T2和T2间期值的差异，采用Pearson相关系数分析其倒数之间的相关性。 ACL断裂患者胫股关节内外侧全层和浅层T2和T2峰值均较高。同时，患者在外侧胫股关节深层表现出较高的T2峰值。浅表LT中T2和T2值升高的百分比最为显著（20.738%、17.525%）。T_2比值的倒数与T_2比值的倒数相关（r = 0.886，P < 0.001）。 急性ACL断裂后，膝关节软骨可发生早期退变，尤其是LT的浅层，T_2磁共振成像对软骨深层的检测可能比T_2磁共振成像更敏感。
To quantitatively assess changes in cartilage matrix after acute anterior cruciate ligament (ACL) rupture using T2- and T2⁎-mapping and analyze the correlation between the results of both methods. Twenty-three patients and 23 healthy controls were enrolled and underwent quantitative MRI examination. The knee cartilage was segmented into six compartments, including lateral femur (LF), lateral tibia (LT), medial femur (MF), medial tibia (MT), trochlea (Tr), and patella (Pa). T2 and T2⁎ values were measured in full-thickness as well as superficial and deep layers of each cartilage compartment. Differences of T2 and T2⁎ values between patients and controls were compared using unpaired Student's t-test, and the correlation between their reciprocals was analyzed using Pearson's correlation coefficient. ACL-ruptured patients showed higher T2 and T2⁎ values in full-thickness and superficial layers of medial and lateral tibiofemoral joint. Meanwhile, patients exhibited higher T2⁎ values in deep layers of lateral tibiofemoral joint. The elevated percentages of T2 and T2⁎ value in superficial LT were most significant (20.738%, 17.525%). The reciprocal of T2⁎ value was correlated with that of T2 value (r = 0.886, P < 0.001). The early degeneration could occur in various knee cartilage compartments after acute ACL rupture, especially in the superficial layer of LT. T2⁎-mapping might be more sensitive in detecting deep layer of cartilage than T2-mapping.
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影响因子：
4.4
作者：
Breitenseher, Martin J.;Mayerhoefer, Marius E.
通讯作者：
Mayerhoefer, Marius E.
影响因子：
19.7
作者：
Mosher, TJ;Dardzinski, BJ;Smith, MB
通讯作者：
Smith, MB
影响因子：
3.8
作者：
Zantop, Thore;Petersen, Wolf;Fu, Freddie H.
通讯作者：
Fu, Freddie H.
DOI：
10.1016/j.arthro.2013.09.075
发表时间：
2013-12-01
影响因子：
4.7
作者：
Li, Hong;Tao, Hongyue;Chen, Shiyi
通讯作者：
Chen, Shiyi
影响因子：
2.1
作者：
Murphy, BJ
通讯作者：
Murphy, BJ