Association of ADAM10 gene variants with sporadic Parkinson's disease in Chinese Han population

Association of ADAM10 gene variants with sporadic Parkinson's disease in Chinese Han population
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ADAM10基因变异与中国汉族人群散发性帕金森病的关联

DOI:
10.1002/jgm.3319
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发表时间:
2021-02
影响因子:
3.5
通讯作者:
Xu Pingyi
Xu Pingyi
中科院分区:
医学4区
文献类型:
--
作者:
Zhou Miaomiao;Lin Yuwan;Lu Lin;Zhang Zhiling;Guo Wenyuan;Peng Guoyou;Zhang Wenlong;Zhu Ziting;Wu Zhuohua;Mo Mingshu;Yang Xinling;Zhu Xiaoqin;Chen Chaojun;Chen Xiang;Xu Pingyi

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帕金森病(Parkinson's disease,PD)是世界范围内第二大常见的神经退行性疾病。遗传因素在PD风险中起重要作用。在高加索人群中,ADAM 10的rs653765和rs 514049与阿尔茨海默病(AD)相关;
Parkinson's disease (PD) is the second most common neurodegenerative disease worldwide. Genetic factors play important roles in PD risk. rs653765 and rs514049 of ADAM10 were reported to be associated with Alzheimer's disease (AD) in Caucasian population;
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