Image enhancement of severely hypoperfused myocardia for computation of tomographic ejection fraction.
Image enhancement of severely hypoperfused myocardia for computation of tomographic ejection fraction.
复制标题
严重低灌注心肌的图像增强，用于计算断层摄影射血分数。
DOI：
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复制
发表时间：
1997
影响因子：
9.3
通讯作者：
Marvin Friedman
中科院分区：
文献类型：
--
作者：
Kenneth Nichols;Depuey Eg;Alan Rozanski;H. Salensky;Marvin Friedman
未标记
从99 mTc-sestamibi心肌灌注门控断层扫描计算的射血分数已被证明具有高度的准确性和可重复性。尽管自动算法似乎为广泛的心脏疾病患者提供了合理的内皮轮廓，但在严重灌注不足的情况下，有必要手动调整对比度和亮度以判断边界是否正确或必须改变。
方法
根据广泛、严重的心肌灌注缺损，为116项研究生成了心室中部水平和垂直长轴门控断层图像。自动化软件将电影断层图像转换成图像，显示整个心动周期心肌的均匀外观。将转换后的图像引入边缘检测算法，用于随后计算心室容积和射血分数。
结果
线性回归分析表明，射血分数（r = 0.95）和体积（r = 0.98）具有良好的观察者内重现性。射血分数（r = 0.86）和体积（r = 0.94）与专家手册图纸中的值也有很好的一致性。在一个22例患者的亚组中，来自转换图像的自动射血分数与独立首过值（r = 0.90）的一致性优于来自原始数据的手动测量值（r = 0.85）。
结论
图像增强算法成功地提供了准确的，可重复的门控SPECT射血分数在最困难的一类患者表现出严重的低灌注。
UNLABELLED
Ejection fractions computed from 99mTc-sestamibi myocardial perfusion gated tomograms have demonstrated a high degree of accuracy and reproducibility. Although automated algorithms appear to provide reasonable endocardial outlines for patients over a broad spectrum of cardiac diseases, in cases of severe hypoperfusion, it is necessary to manually adjust contrast and brightness to judge whether borders are correct or must be altered.
METHODS
Midventricular horizontal and vertical long axis gated tomograms were generated for 116 studies chosen on the basis of extensive, severe myocardial perfusion defects. Automated software transformed cinematic tomograms into images demonstrating uniform appearance of the myocardium throughout the cardiac cycle. Transformed images were introduced to edge detection algorithms for subsequent calculation of ventricular volumes and ejection fractions.
RESULTS
Linear regression analysis demonstrated excellent intraobserver reproducibility for ejection fractions (r = 0.95) and volumes (r = 0.98). There was also good agreement of ejection fractions (r = 0.86) and volumes (r = 0.94) with values derived from an expert's manual drawings. In a subgroup of 22 patients, automated ejection fractions from transformed images demonstrated better agreement with independent first-pass values (r = 0.90) than did manual measurements derived from original data (r = 0.85).
CONCLUSION
Image enhancement algorithms succeeded in providing accurate, reproducible gated SPECT ejection fractions in the most difficult class of patients exhibiting severe hypoperfusion.
定量当天休息压力 technetium-99m-sestamibi SPECT：压力正常限度和异常标准的定义和验证。
DOI：
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发表时间：
1993
期刊：
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
影响因子：
--
作者：
VanTrain,KF;Areeda,J;Garcia,EV;Cooke,CD;Maddahi,J;Kiat,H;Germano,G;Silagan,G;Folks,R;Berman,DS
通讯作者：
Berman,DS
DOI：
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发表时间：
1995-11
期刊：
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
影响因子：
--
作者：
G. Germano;H. Kiat;P. Kavanagh;M. Moriel;M. Mazzanti;H. Su;K. V. Train;D. Berman
通讯作者：
G. Germano;H. Kiat;P. Kavanagh;M. Moriel;M. Mazzanti;H. Su;K. V. Train;D. Berman
使用快速傅立叶变换近似确定计算收缩期壁增厚的准确性：基于犬和患者数据的模拟研究。
DOI：
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发表时间：
1994
期刊：
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
影响因子：
--
作者：
Cooke,CD;Garcia,EV;Cullom,SJ;Faber,TL;Pettigrew,RI
通讯作者：
Pettigrew,RI