CoMet--a web server for comparative functional profiling of metagenomes.
CoMet--a web server for comparative functional profiling of metagenomes.
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DOI:
10.1093/nar/gkr388
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发表时间:
2011-07
影响因子:
14.9
通讯作者:
Meinicke P
中科院分区:
文献类型:
--
作者:
Lingner T;Asshauer KP;Schreiber F;Meinicke P
Analyzing the functional potential of newly sequenced genomes and metagenomes has become a common task in biomedical and biological research. With the advent of high-throughput sequencing technologies comparative metagenomics opens the way to elucidate the genetically determined similarities and differences of complex microbial communities. We developed the web server ‘CoMet’ (http://comet.gobics.de), which provides an easy-to-use comparative metagenomics platform that is well-suitable for the analysis of large collections of metagenomic short read data. CoMet combines the ORF finding and subsequent assignment of protein sequences to Pfam domain families with a comparative statistical analysis. Besides comprehensive tabular data files, the CoMet server also provides visually interpretable output in terms of hierarchical clustering and multi-dimensional scaling plots and thus allows a quick overview of a given set of metagenomic samples.
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影响因子:
3
作者:
Rodriguez-Brito B;Rohwer F;Edwards RA
通讯作者:
Edwards RA
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Goll, Johannes;Rusch, Douglas B.;Yooseph, Shibu
通讯作者:
Yooseph, Shibu
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Finn RD;Mistry J;Tate J;Coggill P;Heger A;Pollington JE;Gavin OL;Gunasekaran P;Ceric G;Forslund K;Holm L;Sonnhammer EL;Eddy SR;Bateman A
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Bateman A
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Meyer, F.;Paarmann, D.;Edwards, R. A.
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Edwards, R. A.
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9.9
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Kunin, Victor;Raes, Jeroen;Harris, J Kirk;Spear, John R;Walker, Jeffrey J;Ivanova, Natalia;von Mering, Christian;Bebout, Brad M;Pace, Norman R;Bork, Peer;Hugenholtz, Philip
通讯作者:
Hugenholtz, Philip