Detection of peripheral nerve and skeletal muscle action currents using magnetic resonance imaging.

Detection of peripheral nerve and skeletal muscle action currents using magnetic resonance imaging.
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DOI:
10.1007/s10439-009-9762-6
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发表时间:
2009-11
影响因子:
3.8
通讯作者:
Roth, Bradley J.
Roth, Bradley J.
中科院分区:
工程技术2区
文献类型:
--
作者:
Wijesinghe, Ranjith S.;Roth, Bradley J.

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许多研究人员尝试使用磁共振成像(MRI)直接检测神经电流。周围神经或骨骼肌的动作电流会产生自己的磁场,导致自旋相位发生变化。我们在本文中的目标是使用测量的神经或肌肉磁场来估计磁共振信号中产生的相移。我们检查了四种情况:鱿鱼巨轴突、青蛙坐骨神经、人类正中神经和大鼠 EDL 肌肉。在每种情况下,相移都远小于十分之一度,并且用当前技术很难测量。
Many researchers have attempted to detect neural currents directly using magnetic resonance imaging (MRI). The action currents of a peripheral nerve or skeletal muscle create their own magnetic field that can cause the phase of the spins to change. Our goal in this paper is to use the measured magnetic field of a nerve or muscle to estimate the resulting phase shift in the magnetic resonance signal. We examine four cases: the squid giant axon, the frog sciatic nerve, the human median nerve, and the rat EDL muscle. In each case, the phase shift is much less than one tenth of one degree, and will be very difficult to measure with current technology.
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