The Diagnosis and Treatment of Local Complications of Acute Necrotizing Pancreatitis in China: A National Survey.

The Diagnosis and Treatment of Local Complications of Acute Necrotizing Pancreatitis in China: A National Survey.
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中国急性坏死性胰腺炎局部并发症的诊断和治疗:全国调查

DOI:
10.1155/2021/6611149
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发表时间:
2021
影响因子:
2
通讯作者:
Chinese Acute Pancreatitis Clinical Trials Group Capctg
Chinese Acute Pancreatitis Clinical Trials Group Capctg
中科院分区:
医学4区
文献类型:
--
作者:
Dong X;Mao W;Ke L;Gao L;Zhou J;Ye B;Li G;Phillips A;Tong Z;Windsor J;Li W;Chinese Acute Pancreatitis Clinical Trials Group Capctg

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背景急性坏死性胰腺炎(ANP)的最佳治疗策略尚有争议,目前对中国指南的依从性尚不清楚。在本研究中,我们对《中国》中的这一主题进行了全国性的调查。方法通过全国协作网络发放关于ANP局部并发症诊断和治疗的在线问卷。根据修订的亚特兰大分类定义局部和全身并发症。结果中国所在的30/34个省份的208家医院,394名开通了沪港通的医院,共有321名受访者,应答率为81%。临床症状(70/321,22%)、器官衰竭(82/321,26%)、影像改变(84/321,26%)和细针抽吸(51/321,16%)对感染性胰腺坏死(IPN)的早期诊断缺乏共识。IPN患者普遍采用“阶梯式”治疗(294/321,92%)。大多数受访者(229/321,71%)根据临床情况、CT成像或实验室指标决定是否进行初步干预(未确认/怀疑感染)。结论“阶梯式”手术虽然已被广泛采用,但在感染的诊断、引流的最佳时机和早期干预的适应证等方面仍存在较大差异。
Background The optimal management strategy in acute necrotizing pancreatitis (ANP) is debated, and compliance with current guidelines in China is not known. In this study, we performed a national survey on this topic in China. Methods An online questionnaire about the diagnosis and treatment of local complications of ANP was distributed through a national collaborative network. The local and systemic complications were defined according to the Revised Atlanta Classification. Results There were 321 survey respondents from the 394 who opened the link (response rate 81%) from 208 hospitals located in 30/34 provinces across China. There was a lack of consensus in terms of early diagnosis of infected pancreatic necrosis (IPN) as the respondents chose to depend on clinical symptoms (70/321, 22%), organ failure (82/321, 26%), imaging changes (84/321, 26%), and fine needle aspiration (51/321, 16%), respectively. A “step-up” approach has been widely adopted in patients with IPN (294/321, 92%). The decision for initial intervention (without confirmed/suspected infection) was based on clinical condition, CT imaging, or laboratory indicators for most respondents (229/321, 71%). Conclusion While the “step-up” approach has been widely adopted, there is still significant variation in regard to the diagnosis of infection, the best timing for drainage, and the indications for early intervention.
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