Reduction in intraocular pressure after cataract extraction: the Ocular Hypertension Treatment Study.
Reduction in intraocular pressure after cataract extraction: the Ocular Hypertension Treatment Study.
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DOI：
10.1016/j.ophtha.2012.02.050
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发表时间：
2012-09
期刊：
影响因子：
13.7
通讯作者：
Ocular Hypertension Treatment Study Group
中科院分区：
文献类型：
--
作者：
Mansberger SL;Gordon MO;Jampel H;Bhorade A;Brandt JD;Wilson B;Kass MA;Ocular Hypertension Treatment Study Group
确定高眼压治疗研究 (OHTS) 观察组白内障摘除术后眼压 (IOP) 的变化。比较病例系列研究期间至少一只眼睛接受过白内障手术的 42 名参与者（63 只眼）和未接受白内障手术的 743 名参与者（743 只眼）组成的对照组我们将“分割日期”定义为白内障手术组报告白内障手术的研究访视日期和对照组的相应日期。术前眼压定义为分割日期之前最多 3 次就诊的平均眼压。术后 IOP 是最多 3 次就诊的平均 IOP，包括分割日期（0、6 和 12 个月，其中“0 个月”等于分割日期）。在两组中，我们在开始降眼压药物或任何类型的青光眼手术后审查数据。术前和术后眼压的差异。白内障组术后眼压显着低于术前（19.8 ± 3.2 mmHg vs. 23.9 ± 3.2 p<0.001）。术后眼压保持低于术前至少 36 个月。术后眼压较术前平均下降16.5%，39.7%的眼睛术后眼压比术前低≥20%。术前眼压最高的眼睛术后眼压下降幅度更大。在对照组中，相应的平均眼压在分割日期之前为 23.8 ± 3.6，在分割日期之后为 23.4 ± 3.9。白内障手术可长期降低高眼压患者的眼压。
To determine the change in intraocular pressure (IOP) after cataract extraction in the Observation Group of the Ocular Hypertension Treatment Study (OHTS). Comparative case series Forty-two participants (63 eyes) who underwent cataract surgery in at least one eye during the study and a control group of 743 participants (743 eyes) who did not undergo cataract surgery We defined the “split date” as the study visit date that cataract surgery was reported in the cataract surgery group, and a corresponding date in the control group. Preoperative IOP was defined as the mean IOP of up to 3 visits prior to split date. Postoperative IOP was the mean IOP of up to 3 visits including the split date (0, 6, and 12 months with ‘0 months’ equaling the split date). In both groups, we censored data after initiation of ocular hypotensive medication, or glaucoma surgery of any kind. Difference in preoperative and postoperative IOP. In the cataract group, postoperative IOP was significantly lower than the preoperative IOP (19.8 ± 3.2 mmHg vs. 23.9 ± 3.2 p<0.001). The postoperative IOP remained lower than preoperative IOP for at least 36 months. The average decrease in postoperative IOP from preoperative IOP was 16.5%, and 39.7% of eyes had postoperative IOP ≥ 20% below preoperative IOP. A greater reduction in postoperative IOP occurred in the eyes with the highest preoperative IOP. In the control group, the corresponding mean IOP’s were 23.8 ± 3.6 prior to the split date and 23.4 ± 3.9 after the split date. Cataract surgery decreases IOP in ocular hypertensive patients over a long period of time.
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