POTENTIAL, IMPEDANCE, AND RECTIFICATION IN MEMBRANES.
POTENTIAL, IMPEDANCE, AND RECTIFICATION IN MEMBRANES.
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DOI：
10.1085/jgp.27.1.37
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发表时间：
1943-09-20
期刊：
影响因子：
--
通讯作者：
Goldman DE
中科院分区：
文献类型：
--
作者：
Goldman DE
已经对许多人造膜进行了阻抗和电位测量。阻抗变化被确定为电流和环境溶液的组成的函数。结果表明，整流是存在于不对称的系统，它与膜电位增加。在不同浓度的相同盐的溶液对的行为已经形成了研究的基础，虽然在相同浓度的不同盐的一些实验给出了与所得出的结论一致的结果。一个理论的图片已经提出的基础上使用的一般动力学方程的离子运动扩散和电力的影响下，并考虑可能的膜结构。方程已经解决了两个非常简单的情况下，一个基于微观电中性的假设，和其他假设的恒定电场。后者被发现给更好的结果比前者在解释数据的潜力和整流，显示协议，但是，正确的数量级。虽然有迹象表明，仔细处理边界条件可能会导致与实验更好的一致性，但由于现有的数据不够完整或可重复，因此没有尝试进行这项工作。第二个理论的情况下，鱿鱼巨大的轴突的应用程序已经取得了定性协议的整流性能和非常好的协议与膜电位数据。
Impedance and potential measurements have been made on a number of artificial membranes. Impedance changes were determined as functions of current and of the composition of the environmental solutions. It was shown that rectification is present in asymmetrical systems and that it increases with the membrane potential. The behavior in pairs of solutions of the same salt at different concentrations has formed the basis for the studies although a few experiments with different salts at the same concentrations gave results consistent with the conclusions drawn. A theoretical picture has been presented based on the use of the general kinetic equations for ion motion under the influence of diffusion and electrical forces and on a consideration of possible membrane structures. The equations have been solved for two very simple cases; one based on the assumption of microscopic electroneutrality, and the other on the assumption of a constant electric field. The latter was found to give better results than the former in interpreting the data on potentials and rectification, showing agreement, however, of the right order of magnitude only. Although the indications are that a careful treatment of boundary conditions may result in better agreement with experiment, no attempt has been made to carry this through since the data now available are not sufficiently complete or reproducible. Applications of the second theoretical case to the squid giant axon have been made showing qualitative agreement with the rectification properties and very good agreement with the membrane potential data.
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影响因子：
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作者：
Bear, RS;Schmitt, FO
通讯作者：
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影响因子：
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作者：
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影响因子：
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影响因子：
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作者：
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影响因子：
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作者：
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