Genetic Architecture of Natural Variation Underlying Adult Foraging Behavior That Is Essential for Survival of Drosophila melanogaster.
Genetic Architecture of Natural Variation Underlying Adult Foraging Behavior That Is Essential for Survival of Drosophila melanogaster.
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成虫觅食行为背后的自然变异的遗传结构对于果蝇的生存至关重要。
DOI:
10.1093/gbe/evx089
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发表时间:
2017
影响因子:
3.3
通讯作者:
Zhuang,Xiaoxi
中科院分区:
文献类型:
--
作者:
Lee,YuhChwenG;Yang,Qian;Chi,Wanhao;Turkson,SusieA;Du,WeiA;Kemkemer,Claus;Zeng,Zhao-Bang;Long,Manyuan;Zhuang,Xiaoxi
Foraging behavior is critical for the fitness of individuals. However, the genetic basis of variation in foraging behavior and the evolutionary forces underlying such natural variation have rarely been investigated. We developed a systematic approach to assay the variation in survival rate in a foraging environment for adult flies derived from a wildDrosophila melanogasterpopulation. Despite being such an essential trait, there is substantial variation of foraging behavior amongD. melanogasterstrains. Importantly, we provided the first evaluation of the potential caveats of using inbredDrosophilastrains to perform genome-wide association studies on life-history traits, and concluded that inbreeding depression is unlikely a major contributor for the observed large variation in adult foraging behavior. We found that adult foraging behavior has a strong genetic component and, unlike larval foraging behavior, depends on multiple loci. Identified candidate genes are enriched in those with high expression in adult heads and, demonstrated by expression knock down assay, are involved in maintaining normal functions of the nervous system. Our study not only identified candidate genes for foraging behavior that is relevant to individual fitness, but also shed light on the initial stage underlying the evolution of the behavior.
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影响因子:
39.2
作者:
Robert P. Kimberly;John R. Gill;R. Bowden;H. R. Keiser;Paul H. Plotz
通讯作者:
Paul H. Plotz
影响因子:
64.8
作者:
R. Imhoff
通讯作者:
R. Imhoff
DOI:
--
发表时间:
1977
期刊:
Journal of Physiology
影响因子:
--
作者:
M. Harper;E. Mackenzie
通讯作者:
E. Mackenzie
DOI:
--
发表时间:
1983
期刊:
影响因子:
--
作者:
F. Clerck;J. M. Nueten
通讯作者:
J. M. Nueten
影响因子:
5
作者:
R. Brazenor;J. Angus
通讯作者:
J. Angus