High Risk of Mother‐to‐Child Transmission of HTLV‐I in p40tax Antibody‐positive Mothers

High Risk of Mother‐to‐Child Transmission of HTLV‐I in p40tax Antibody‐positive Mothers
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p40tax 抗体阳性母亲中 HTLV-I 母婴传播的高风险

DOI:
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发表时间:
1989
期刊:
Japanese journal of cancer research : Gann
影响因子:
--
通讯作者:
I. Miyoshi
I. Miyoshi
中科院分区:
--
文献类型:
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作者:
T. Sawada;J. Tohmatsu;T. Obara;A. Koide;S. Kamihira;M. Ichimaru;S. Kashiwagi;W. Kajiyama;N. Matsumura;K. Kinoshita;M. Yano;K. Yamaguchi;T. Kiyokawa;K. Takatsuki;H. Taguchi;I. Miyoshi

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A new enzyme‐linked immunosorbent assay (ELISA) for detecting the antibody to a human T‐lymphotropic virus type I (HTLV‐I) tax gene product, p40tax, has been developed. By this ELISA method, we have investigated the relationship between the presence of p40tax antibody in HTLV‐I‐infected mothers and the virus transmission rate from mothers to their children. The rate of mother‐to‐child transmission of HTLV‐I was higher in P40tax antibody‐positive mothers than in antibody‐negative ones. Thus, the presence of P40tax antibody may indicate an increased risk of vertical transmission of HTLV‐I.
新型 HTLV 感染细胞系的表征。
DOI: --
发表时间: 1984
期刊: Blood
影响因子: 20.3
作者:
Koeffler,HP;Chen,IS;Golde,DW
通讯作者: Golde,DW
DOI: 10.1126/science.6089351
发表时间: 1984-01-01
期刊: SCIENCE
影响因子: 56.9
作者:
SLAMON, DJ;SHIMOTOHNO, K;CHEN, ISY
通讯作者: CHEN, ISY