High Risk of Mother‐to‐Child Transmission of HTLV‐I in p40tax Antibody‐positive Mothers
High Risk of Mother‐to‐Child Transmission of HTLV‐I in p40tax Antibody‐positive Mothers
复制标题
p40tax 抗体阳性母亲中 HTLV-I 母婴传播的高风险
DOI:
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发表时间:
1989
期刊:
影响因子:
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通讯作者:
I. Miyoshi
中科院分区:
文献类型:
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作者:
T. Sawada;J. Tohmatsu;T. Obara;A. Koide;S. Kamihira;M. Ichimaru;S. Kashiwagi;W. Kajiyama;N. Matsumura;K. Kinoshita;M. Yano;K. Yamaguchi;T. Kiyokawa;K. Takatsuki;H. Taguchi;I. Miyoshi
A new enzyme‐linked immunosorbent assay (ELISA) for detecting the antibody to a human T‐lymphotropic virus type I (HTLV‐I) tax gene product, p40tax, has been developed. By this ELISA method, we have investigated the relationship between the presence of p40tax antibody in HTLV‐I‐infected mothers and the virus transmission rate from mothers to their children. The rate of mother‐to‐child transmission of HTLV‐I was higher in P40tax antibody‐positive mothers than in antibody‐negative ones. Thus, the presence of P40tax antibody may indicate an increased risk of vertical transmission of HTLV‐I.
影响因子:
20.3
作者:
Koeffler,HP;Chen,IS;Golde,DW
通讯作者:
Golde,DW
影响因子:
56.9
作者:
SLAMON, DJ;SHIMOTOHNO, K;CHEN, ISY
通讯作者:
CHEN, ISY