The amplitude of quantal currents is reduced during short-term depression at neuromuscular synapses in Drosophila

The amplitude of quantal currents is reduced during short-term depression at neuromuscular synapses in Drosophila
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果蝇神经肌肉突触的短期抑制期间量子电流的幅度降低

DOI:
10.1016/s0304-3940(97)00167-5
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发表时间:
1997
影响因子:
2.5
通讯作者:
J. Dudel
J. Dudel
中科院分区:
医学4区
文献类型:
--
作者:
H. Adelsberger;M. Heckmann;J. Dudel

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Focal extracellular excitatory postsynaptic currents were recorded to investigate short-term depression at glutamatergic Drosophila neuromuscular synapses. The amplitudes of quantal excitatory postsynaptic currents (qEPSCs) elicited before and after depolarizations eliciting large release were compared. Depression reduced the amplitude of the qEPSCs to 0.65±0.14 of control. Recovery from depression and of the receptor channels from desensitization follow a similar time course. Thus receptor desensitization seems to be involved in short-term depression at Drosophila neuromuscular junctions.
DOI: 10.1126/science.1681589
发表时间: 1991-10-11
期刊: SCIENCE
影响因子: 56.9
作者:
TANG, CM;SHI, QY;LYNCH, G
通讯作者: LYNCH, G