Antiretroviral Therapy (ART) Adherence and Prenatal Alcohol Use among Women Who Are Pregnant with HIV in South Africa.

Antiretroviral Therapy (ART) Adherence and Prenatal Alcohol Use among Women Who Are Pregnant with HIV in South Africa.
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DOI:
10.3390/ijerph18147446
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发表时间:
2021-07-13
影响因子:
--
通讯作者:
Wechsberg WM
Wechsberg WM
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Washio Y;Browne FA;Ndirangu J;Kline TL;Wechsberg WM

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这份简短的报告强调需要关注使用酒精或其他药物的怀孕艾滋病毒女性。最近完成的一项实施科学研究测试了一种以性别为中心的行为干预措施,即妇女健康合作社 (WHC),以提高艾滋病毒感染女性的抗逆转录病毒治疗 (ART) 依从性并减少饮酒。该研究确定了 33 名在基线评估时妊娠测试结果呈阳性的参与者,其中 5 名参与者在研究的 6 个月期间仍然怀孕。在基线评估的 33 名怀孕参与者中,55% 的人报告过去一个月饮酒,27% 的人报告有身体虐待史,12% 的人报告有性虐待史。五名在 6 个月时仍怀孕的妇女表现出 ART 依从性有所提高,并减少了产前饮酒。以性别为中心的 WHC 干预措施有望作为一种具有成本效益、可持续的行为干预措施来解决这些交叉的流行病问题。未来的研究应侧重于确定使用酒精或其他药物的怀孕艾滋病毒女性的需求,并制定量身定制的循证行为干预措施,例如预防胎儿酒精谱系障碍的 WHC,此外还应提高这一关键女性群体的抗逆转录病毒治疗依从性并减轻社会经济负担。
This brief report emphasizes the need to focus on women with HIV who are pregnant who use alcohol or other drugs. A recently completed implementation science study tested a gender-focused behavioral intervention, the Women’s Health CoOp (WHC), to improve antiretroviral therapy (ART) adherence and reduce alcohol use among women with HIV. The study identified 33 participants who had a positive pregnancy test result at the baseline assessment, of whom five participants remained pregnant during the 6-month duration of the study. Of the 33 pregnant participants at the baseline assessment, 55% reported past-month alcohol use, with 27% reporting a history of physical abuse and 12% reporting a history of sexual abuse. The five women who remained pregnant at 6 months showed improved ART adherence and reduced prenatal alcohol use. The gender-focused WHC intervention shows promise as a cost-effective, sustainable, behavioral intervention to address these intersecting syndemic issues. Future research should focus on identifying the needs of women with HIV who are pregnant who use alcohol or other drugs and developing tailored evidence-based behavioral interventions such as the WHC for preventing FASD in addition to improving ART adherence in this key population of women and reducing the economic burden on society.
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