Sequential processing deficit as a shared persisting biomarker in dyslexia and childhood apraxia of speech.
Sequential processing deficit as a shared persisting biomarker in dyslexia and childhood apraxia of speech.
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DOI：
10.1080/02699206.2017.1375560
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发表时间：
2018
影响因子：
1.2
通讯作者：
Stoel-Gammon C
中科院分区：
文献类型：
--
作者：
Peter B;Lancaster H;Vose C;Middleton K;Stoel-Gammon C
本研究的目的是探讨阅读障碍患者和儿童言语失用症患者在处理顺序信息时存在潜在的持续性缺陷这一假设。损伤程度(感觉编码、记忆、提取、运动规划/编程)也被调查。受试者包括22名患有阅读障碍的成年人，10名可能有儿童言语失用史(PhCAS)的成年人，以及22名典型的对照组。所有参与者都完成了非单词重复、多音节真实单词重复和非单词解码任务。运用语音过程分析方法，将错误分为顺序性错误和代入性错误。患有阅读障碍的成年人和患有phCAS的成年人表现出持续的非单词重复缺陷。在所有三项任务中，两个障碍组的成年人在两个类别的错误中都比对照组产生了更多的错误，但在非单词重复任务中，排序错误比替换错误多得不成比例。在真实单词重复任务中，phCAS产生的排序错误最多，而在非单词解码任务中，阅读障碍组产生的排序错误最多。在多音节运动语音任务中的表现，相对于单音节条件，与非单词重复过程中的排序错误成分相关。结果表明，在语言和运动言语任务中，阅读障碍组和phCAS组存在共同的持续性顺序加工缺陷。在这两组障碍中都发现了感觉编码、短期记忆和运动规划/编程方面的障碍的证据。未来的研究应该调查针对交叉模式治疗效果的预防性和针对性干预的临床应用。
The purpose of this study was to investigate the hypothesis that individuals with dyslexia and individuals with childhood apraxia of speech share an underlying persisting deficit in processing sequential information. Levels of impairment (sensory encoding, memory, retrieval, motor planning/programming) were also investigated. Participants were 22 adults with dyslexia, 10 adults with a probable history of childhood apraxia of speech (phCAS), and 22 typical controls. All participants completed nonword repetition, multisyllabic real word repetition, and nonword decoding tasks. Using phonological process analysis, errors were classified as sequence or substitution errors. Adults with dyslexia and adults with phCAS showed evidence of persisting nonword repetition deficits. In all three tasks, the adults in the two disorder groups produced more errors of both classes than the controls, but disproportionally more sequencing than substitution errors during the nonword repetition task. During the real word repetition task, the phCAS produced the most sequencing errors, whereas during the nonword decoding task, the dyslexia group produced the most sequencing errors. Performance during multisyllabic motor speech tasks, relative to monosyllabic conditions, was correlated with the sequencing error component during nonword repetition. Results provide evidence for a shared persisting sequential processing deficit in the dyslexia and phCAS groups during linguistic and motor speech tasks. Evidence for impairments in sensory encoding, short-term memory, and motor planning/programming was found in both disorder groups. Future studies should investigate clinical applications regarding preventative and targeted interventions towards crossmodal treatment effects.
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影响因子：
2.5
作者：
Can, Dilara Deniz;Richards, Todd;Kuhl, Patricia K.
通讯作者：
Kuhl, Patricia K.
DOI：
10.1044/jshr.1504.763
发表时间：
1972-01-01
期刊：
JOURNAL OF SPEECH AND HEARING RESEARCH
影响因子：
--
作者：
FLETCHER, SG
通讯作者：
FLETCHER, SG
DOI：
10.1044/jshd.5403.422
发表时间：
1989-08-01
期刊：
JOURNAL OF SPEECH AND HEARING DISORDERS
影响因子：
--
作者：
CATTS, HW
通讯作者：
CATTS, HW
影响因子：
3
作者：
BLALOCK, JW
通讯作者：
BLALOCK, JW
影响因子：
1.2
作者：
Button L;Peter B;Stoel-Gammon C;Raskind WH
通讯作者：
Raskind WH