Theoretical and Practical Considerations in the Restoration of Function After Stroke
Theoretical and Practical Considerations in the Restoration of Function After Stroke
复制标题
中风后功能恢复的理论和实践思考
DOI：
10.1310/8t1t-etxu-8pdf-9x7f
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发表时间：
2001
影响因子：
2.2
通讯作者：
P. Bach
中科院分区：
文献类型：
--
作者：
P. Bach
卒中后功能恢复包括恢复和代偿两个方面。大脑具有高度的可塑性，可以在受损后进行重组。中风会对大脑造成永久性损伤，因此恢复必须基于相邻、对侧或不同区域的存活细胞的活动。此外，大脑中特定功能的表示通常不限于单个大脑区域。多重表征为大脑重组提供了机会;功能由幸存的大脑结构承担。补偿可以是恢复阶段的最初反应，并且由于形成的新习惯，补偿可能会持续到以后的阶段（正如陶布和其他人的约束疗法研究所建议的那样），因为对大脑的损伤是广泛的，阻碍了恢复，因为继发性病理，如肌腱缩短和肌肉萎缩，不允许大脑重组转化为功能恢复，或者是因为康复不充分（尤其是后期）。
Abstract Recovery of function after stroke appears to include elements of both restoration and compensation. The brain is highly plastic, which allows reorganization after damage. Stroke produces permanent damage to the brain, so recovery must be based on activity in surviving cells that are either adjacent, contralateral, or in a different region. Furthermore, representation of a particular function in the brain is usually not limited to a single brain region. Multiple representation provides the opportunity for brain reorganization; functions are assumed by surviving brain structures. Compensation can be the initial response in the recovery phase and may persist through later phases because of the new habits formed (as the restraint therapy studies of Taub and others would suggest), because the damage to the brain is extensive and hinders restoration, because of secondary pathology, such as tendon shortening and muscle wasting, that does not allow brain reorganization to be translated into functional recovery, or because of inadequate (especially late) rehabilitation.
影响因子：
56.9
作者：
FEENEY, DM;GONZALEZ, A;LAW, WA
通讯作者：
LAW, WA
影响因子：
56.9
作者：
MCBAIN, CJ;TRAYNELIS, SF;DINGLEDINE, R
通讯作者：
DINGLEDINE, R