Distress tolerance to auditory feedback and functional connectivity with the auditory cortex.
Distress tolerance to auditory feedback and functional connectivity with the auditory cortex.
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DOI：
10.1016/j.pscychresns.2018.10.003
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发表时间：
2018-12-30
期刊：
影响因子：
--
通讯作者：
Appelbaum LG
中科院分区：
文献类型：
--
作者：
Addicott MA;Daughters SB;Strauman TJ;Appelbaum LG
痛苦耐受力是为了追求目标而承受负面情感状态的能力。较低的痛苦耐受力可能会使个体倾向于避免或逃避引起情感痛苦的经历，但自下而上产生痛苦的神经机制及其与行为回避的关系尚不清楚。在神经影像扫描期间，健康参与者完成了一项心算任务，分为简单阶段和痛苦阶段，这在认知需求以及积极与消极的听觉反馈方面有所不同。然后，参与者有机会继续玩困境阶段以获得经济奖励，并可以随时退出。持续时间是对痛苦耐受力的衡量。轻松和痛苦阶段激活了听觉皮层和额顶叶区域。使用左侧次级听觉皮层（即颞平面）作为种子区域的基于任务的功能连接分析显示，在痛苦阶段，与额顶叶区域和前岛叶的连接更强。种子区和左前岛叶之间与应激相关的连接与应激耐受性呈负相关。研究结果提供了初步证据，证明前岛叶在自下而上的情感困扰和自上而下的行为回避痛苦之间发挥中介作用。
Distress tolerance is the capacity to withstand negative affective states in pursuit of a goal. Low distress tolerance may bias an individual to avoid or escape experiences that induce affective distress, but the neural mechanisms underlying the bottom-up generation of distress and its relationship to behavioral avoidance are poorly understood. During a neuroimaging scan, healthy participants completed a mental arithmetic task with easy and distress phases, which differed in cognitive demands and positive versus negative auditory feedback. Then, participants were given the opportunity to continue playing the distress phase for a financial bonus and were allowed to quit at any time. The persistence duration was the measure of distress tolerance. The easy and distress phases activated auditory cortices and fronto-parietal regions. A task-based functional connectivity analysis using the left secondary auditory cortex (i.e., planum temporale) as the seed region revealed stronger connectivity to fronto-parietal regions and anterior insula during the distress phase. The distress-related connectivity between the seed region and the left anterior insula was negatively correlated with distress tolerance. The results provide initial evidence of the role of the anterior insula as a mediating link between the bottom-up generation of affective distress and top-down behavioral avoidance of distress.
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DOI：
10.1111/add.13061
发表时间：
2015-12
期刊：
Addiction (Abingdon, England)
影响因子：
--
作者：
Abdolahi A;Williams GC;Benesch CG;Wang HZ;Spitzer EM;Scott BE;Block RC;van Wijngaarden E
通讯作者：
van Wijngaarden E
影响因子：
10.6
作者：
Caria, Andrea;Sitaram, Ranganatha;Birbaumer, Niels
通讯作者：
Birbaumer, Niels
影响因子：
4.1
作者：
Feldner, MT;Zvolensky, MJ;Spira, AP
通讯作者：
Spira, AP
影响因子：
4.7
作者：
Brown, Richard A.;Lejuez, C. W.;Price, Lawrence H.
通讯作者：
Price, Lawrence H.
影响因子：
4.2
作者：
Bornovalova, Marina A.;Gratz, Kim L.;Daughters, Stacey B.;Hunt, Elizabeth D.;Lejuez, C. W.
通讯作者：
Lejuez, C. W.