A histopathological study of the effects of low-power laser irradiation on wound healing of exposed dental pulp tissues in dogs, with special reference to lectins and collagens.
A histopathological study of the effects of low-power laser irradiation on wound healing of exposed dental pulp tissues in dogs, with special reference to lectins and collagens.
复制标题
低功率激光照射对狗暴露牙髓组织伤口愈合影响的组织病理学研究，特别是凝集素和胶原蛋白。
DOI：
10.1016/s0099-2399(98)80181-7
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发表时间：
1998
影响因子：
4.2
通讯作者：
T. Utsunomiya
中科院分区：
文献类型：
--
作者：
T. Utsunomiya
本实验研究了低功率激光照射对狗裸露牙髓组织的影响。用镓铝砷半导体激光(300 MW)照射牙髓裸露表面，观察术后1、3、7wk的组织病理学变化。此外，还观察了凝集素(刀豆蛋白A、扁豆凝集素、花生凝集素、蓖麻凝集素I、大豆凝集素、大豆凝集素、小麦胚凝集素)与I、III、V型胶原的结合方式和分布，以确定创面愈合的组织化学和免疫组织化学性质。照射组牙本质桥形成的纤维基质形成和持续变化早于未照射对照组(术后1wk)。凝集素组织化学和胶原免疫组织化学显示刀豆蛋白A、花生凝集素、麦芽凝集素和胶原(I、III、V型)分布于纤维基质和牙本质桥中。这些凝集素和胶原蛋白的表达在激光照射组比对照组更早出现。这些结果表明，激光照射促进了牙髓创面的愈合以及凝集素和胶原的表达。此外，D-葡萄糖、D-甘露糖、N-乙酰-D-氨基半乳糖和N-乙酰-神经氨酸结合糖以及I型、III型和V型胶原在牙髓创面的愈合中起着重要作用。
This study investigated the effects of low-power laser irradiation on exposed pulp tissue in dogs. Gallium-aluminium-arsenide diode laser (300 mW) irradiation was applied to the exposed surface of the pulp, and histopathological changes were observed at 1, 3, and 7 wk after the operation. In addition, the lectin (concanavalin A, Dolichos biflorus agglutinin, peanut agglutinin, Ricinus communis agglutinin I, soybean agglutinin, Ulex europeus agglutinin I, and wheat germ agglutinin) binding pattern and distribution of collagens (type I, III, and V) were examined to determine the histochemical and immunohistochemical nature of wound healing. The fibrous matrix formation and the continuing changes in the dentin bridge formation of the irradiation group were observed earlier (1 wk after the operation) than in the nonirradiation control group. Lectin histochemistry and collagen immunohistochemistry showed that concanavalin A, peanut agglutinin, wheat germ agglutinin, and collagens (types I, III, and V) were distributed in the fibrous matrix and dentin bridge. The expression of these lectins and collagens occurred earlier in the laser irradiation group than in the control group. These results suggest that laser irradiation accelerates wound healing of the pulp and the expression of the lectins and collagens. Furthermore, d-glucose-, d-mannose-, N-acetyl-d-galactosamine-, and N-acetyl-neuraminic acid-binding sugars and type I, III, and V collagens play an important role in the healing of pulp wounds.
证明用氦氖激光治疗的皮肤伤口中 I 型和 III 型原胶原 mRNA 水平升高。
DOI：
10.1016/s0006-291x(86)80399-0
发表时间：
1986
影响因子：
3.1
作者：
Saperia,D;Glassberg,E;Lyons,RF;Abergel,RP;Baneux,P;Castel,JC;Dwyer,RM;Uitto,J
通讯作者：
Uitto,J
牛牙髓胶原蛋白：III 型和 V 型胶原蛋白的表征。
影响因子：
3
作者：
Tsuzaki,M;Yamauchi,M;Mechanic,GL
通讯作者：
Mechanic,GL