Accuracy and cut-off point selection in three-class classification problems using a generalization of the Youden index.

Accuracy and cut-off point selection in three-class classification problems using a generalization of the Youden index.
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DOI:
10.1002/sim.4044
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发表时间:
2010-12-10
影响因子:
2
通讯作者:
Yiannoutsos, Constantin T.
Yiannoutsos, Constantin T.
中科院分区:
医学3区
文献类型:
--
作者:
Nakas, Christos T.;Alonzo, Todd A.;Yiannoutsos, Constantin T.

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我们研究的指标J3,定义为准确性,或最大的正确分类,对于一个给定的三类分类问题的属性。具体而言,使用J3可以评估三个分布之间的区分,并获得最佳的一对截止点c1 < c2,在这个意义上,正确分类比例的总和将被最大化。它也是Youden指标在三类问题中的推广。参数和非参数估计和检验的方法被认为是和方法适用于数据从MRS研究艾滋病毒患者。
We study properties of the index J3, defined as the accuracy, or the maximum correct classification, for a given three-class classification problem. Specifically, using J3 one can assess the discrimination between the three distributions and obtain an optimal pair of cut-off points c1 < c2 in the sense that the sum of the correct classification proportions will be maximized. It also serves as the generalization of the Youden index in three-class problems. Parametric and non-parametric approaches for estimation and testing are considered and methods are applied to data from an MRS study on HIV patients.
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