Knocking down a pathway to build it up
Knocking down a pathway to build it up
复制标题
拆除一条道路来建立它
DOI：
10.1016/0168-9525(94)90080-9
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发表时间：
1994
影响因子：
11.4
通讯作者：
P. Kayne
中科院分区：
文献类型：
--
作者：
P. Kayne
lhc, tam 2. Vulval development begins when an inductive signal, produced by the anchor cell, is received by the vulval precursor cells (VPCs). The VPCs are nolrnaliy kept quiescent by an inhibitory signal (represented as a barred line) produced by the surrounding epidermis. The lateral signals (represented by arrows) are invoh'ed in the choice between the two vulval cell fates. activated Ras. Indeed, both groups identified many such suppressors. The first such alleles characterized and described lay, perhaps not surprisingly, in a gene that encodes MAP kinase, and is named sur-1 (Ref. 2) or mpk-1 (Ref. 3). By analogy with other pathways, it has been assumed that a MAP kinase would play an important role in vulval development. Indeed,
秀丽隐杆线虫的细胞间信号传导和信号转导。
影响因子：
11.1
作者：
Sternberg,PW
通讯作者：
Sternberg,PW